GDF-15 Suppresses Puromycin Aminonucleoside-Induced Podocyte Injury by Reducing Endoplasmic Reticulum Stress and Glomerular Inflammation.
GDF15
endoplasmic reticulum stress
glomerular inflammation
podocytes
podocytopathies
Journal
Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052
Informations de publication
Date de publication:
05 Apr 2024
05 Apr 2024
Historique:
received:
12
02
2024
revised:
22
03
2024
accepted:
30
03
2024
medline:
12
4
2024
pubmed:
12
4
2024
entrez:
12
4
2024
Statut:
epublish
Résumé
GDF15, also known as MIC1, is a member of the TGF-beta superfamily. Previous studies reported elevated serum levels of GDF15 in patients with kidney disorder, and its association with kidney disease progression, while other studies identified GDF15 to have protective effects. To investigate the potential protective role of GDF15 on podocytes, we first performed in vitro studies using a
Identifiants
pubmed: 38607075
pii: cells13070637
doi: 10.3390/cells13070637
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM