Airway remodelling in asthma and the epithelium: on the edge of a new era.
Journal
The European respiratory journal
ISSN: 1399-3003
Titre abrégé: Eur Respir J
Pays: England
ID NLM: 8803460
Informations de publication
Date de publication:
Apr 2024
Apr 2024
Historique:
received:
22
09
2023
accepted:
15
02
2024
pubmed:
13
4
2024
medline:
13
4
2024
entrez:
12
4
2024
Statut:
epublish
Résumé
Asthma is a chronic, heterogeneous disease of the airways, often characterised by structural changes known collectively as airway remodelling. In response to environmental insults, including pathogens, allergens and pollutants, the epithelium can initiate remodelling
Identifiants
pubmed: 38609094
pii: 13993003.01619-2023
doi: 10.1183/13993003.01619-2023
pmc: PMC11024394
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright ©The authors 2024.
Déclaration de conflit d'intérêts
Conflict of interest: G. Varricchi has received grants from AstraZeneca. C.E. Brightling has received grants and consultancy fees from 4D Pharma, AstraZeneca, Chiesi, Genentech, GSK, Mologic, Novartis, Regeneron Pharmaceuticals, Roche and Sanofi. C. Grainge has received grants from AstraZeneca and industry-sponsored grants from Boehringer Ingelheim and Cyclopharma. B.N. Lambrecht has received grants from the European Research Council, Ghent University, Research Foundation Flanders and the Flanders Institute of Biotechnology, and has received consulting fees from Argenx, AstraZeneca, GSK and Sanofi. P. Chanez has received consultancy fees from ALK, Almirall, AstraZeneca, Boehringer Ingelheim, Boston Scientific, Centocor, Chiesi, GSK, Johnson & Johnson, MSD, Novartis, Sanofi, SNCF and Teva Pharmaceuticals, has received industry-sponsored grants from ALK, AstraZeneca, Boehringer Ingelheim, Boston Scientific, Centocor, Chiesi, GSK, Novartis, Roche and Teva Pharmaceuticals, and is the president of the scientific committee for Fondation du Souffle.
Références
J Allergy Clin Immunol. 2021 Sep;148(3):790-798
pubmed: 33872652
N Engl J Med. 2021 Oct 28;385(18):1656-1668
pubmed: 34706171
Am J Physiol Lung Cell Mol Physiol. 2005 Jan;288(1):L52-60
pubmed: 15361359
Eur Respir J. 2021 Dec 31;59(1):
pubmed: 34049943
Immun Inflamm Dis. 2021 Sep;9(3):624-627
pubmed: 33960689
J Immunol. 2010 Jun 15;184(12):7134-43
pubmed: 20483734
Nat Immunol. 2002 Jul;3(7):673-80
pubmed: 12055625
Ann Am Thorac Soc. 2018 Nov;15(Suppl 3):S184-S191
pubmed: 30431352
Respir Res. 2016 Sep 22;17(1):119
pubmed: 27658857
Pediatr Allergy Immunol. 2005 Feb;16(1):43-51
pubmed: 15693911
Clin Epigenetics. 2021 Mar 29;13(1):65
pubmed: 33781317
J Immunol. 2007 Jul 15;179(2):1080-7
pubmed: 17617600
N Engl J Med. 2011 May 26;364(21):2006-15
pubmed: 21612469
Pulm Pharmacol Ther. 2019 Oct;58:101836
pubmed: 31473366
Clin Respir J. 2021 Oct;15(10):1027-1045
pubmed: 34097803
Ann Intern Med. 2011 May 3;154(9):573-82
pubmed: 21536936
Eur Respir Rev. 2023 May 17;32(168):
pubmed: 37197769
Front Physiol. 2023 Jan 25;14:1064822
pubmed: 36760534
PLoS One. 2015 Sep 02;10(9):e0136549
pubmed: 26332463
PLoS One. 2012;7(9):e44213
pubmed: 22970180
Eur Respir J. 2015 Dec;46(6):1796-804
pubmed: 26541520
Oncol Lett. 2017 Dec;14(6):7483-7488
pubmed: 29344192
Eur Respir J. 2019 Nov 7;54(5):
pubmed: 31439682
Int J Mol Sci. 2022 Nov 21;23(22):
pubmed: 36430941
Respirology. 2018 Dec;23(12):1138-1145
pubmed: 29943875
Chest. 1997 Apr;111(4):852-7
pubmed: 9106559
J Allergy Clin Immunol Pract. 2019 Jan;7(1):156-164.e1
pubmed: 29800752
N Engl J Med. 2018 Jun 28;378(26):2486-2496
pubmed: 29782217
Front Immunol. 2023 Jul 13;14:1201658
pubmed: 37520564
Sci Rep. 2013;3:2301
pubmed: 23892442
Allergy. 2020 Aug;75(8):1902-1917
pubmed: 32460363
Lancet Respir Med. 2021 May;9(5):441-443
pubmed: 33577751
Thorax. 2013 Jan;68(1):82-90
pubmed: 23093652
Nat Commun. 2021 May 11;12(1):2574
pubmed: 33976140
Exp Lung Res. 2018 Aug;44(6):288-301
pubmed: 30428724
Front Physiol. 2023 Jan 19;14:1113100
pubmed: 36744026
Respirology. 2020 Jun;25(6):603-612
pubmed: 31610614
Eur Respir Rev. 2015 Mar;24(135):30-9
pubmed: 25726552
Clin Rev Allergy Immunol. 2019 Apr;56(2):234-247
pubmed: 30506113
Front Immunol. 2018 Jul 13;9:1595
pubmed: 30057581
Clin Exp Allergy. 2012 May;42(5):638-49
pubmed: 22192725
Cell Biochem Funct. 2013 Aug;31(6):496-503
pubmed: 23192865
Front Immunol. 2023 May 02;14:1190034
pubmed: 37205111
Postepy Dermatol Alergol. 2018 Oct;35(5):462-469
pubmed: 30429702
Am J Respir Cell Mol Biol. 2016 Mar;54(3):350-8
pubmed: 26222011
JCI Insight. 2019 Mar 7;4(5):
pubmed: 30721157
J Allergy Clin Immunol. 2019 Nov;144(5):1242-1253.e7
pubmed: 31082457
J Allergy Clin Immunol. 2020 Jun;145(6):1499-1509
pubmed: 32507228
N Engl J Med. 2014 Sep 25;371(13):1198-207
pubmed: 25199059
Eur Respir J. 2017 May 1;49(5):
pubmed: 28461289
Nat Med. 2012 May 04;18(5):716-25
pubmed: 22561835
J Asthma. 2020 May;57(5):468-477
pubmed: 30905217
N Engl J Med. 2007 Nov 15;357(20):2016-27
pubmed: 18003958
J Allergy Clin Immunol. 2004 Jan;113(1):101-8
pubmed: 14713914
Pediatr Res. 2019 Aug;86(2):181-187
pubmed: 30464333
Front Pharmacol. 2013 Apr 17;4:46
pubmed: 23616768
Cells. 2022 Mar 24;11(7):
pubmed: 35406669
Chest. 2012 Jul;142(1):76-85
pubmed: 22052771
Adv Immunol. 2019;142:1-34
pubmed: 31296301
N Engl J Med. 2021 May 13;384(19):1800-1809
pubmed: 33979488
Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):13132-13137
pubmed: 27799535
Am J Respir Crit Care Med. 2007 Nov 1;176(9):858-64
pubmed: 17702968
Lancet Respir Med. 2019 Jan;7(1):20-34
pubmed: 30552067
Clin Exp Allergy. 2020 Dec;50(12):1342-1351
pubmed: 32909660
Eur Respir Rev. 2020 Aug 4;29(157):
pubmed: 32759373
J Immunol. 2009 Oct 15;183(8):5094-103
pubmed: 19801525
J Allergy Clin Immunol. 2021 Sep;148(3):752-762
pubmed: 33577895
Expert Opin Ther Targets. 2020 Aug;24(8):777-792
pubmed: 32567399
J Immunol. 2014 Apr 15;192(8):3475-87
pubmed: 24623133
Exp Lung Res. 2019 Oct;45(8):221-235
pubmed: 31378088
Clin Exp Allergy. 2017 Dec;47(12):1534-1545
pubmed: 28833774
Blood Adv. 2017 Mar 30;1(10):577-589
pubmed: 29296700
J Allergy Clin Immunol. 2019 Sep;144(3):634-640
pubmed: 31376405
Int Rev Immunol. 1998;16(3-4):227-47
pubmed: 9505190
Lancet Respir Med. 2019 Apr;7(4):336-346
pubmed: 30584054
Clin Exp Allergy. 2020 Jul;50(7):780-788
pubmed: 32347992
Am J Respir Crit Care Med. 2001 Nov 15;164(10 Pt 2):S90-4
pubmed: 11734475
Eur Respir J. 2020 Nov 12;56(5):
pubmed: 32586879
NEJM Evid. 2023 Oct;2(10):EVIDoa2300135
pubmed: 38320181
Curr Opin Pulm Med. 2020 Jan;26(1):62-68
pubmed: 31703000
Front Immunol. 2020 Jun 18;11:1134
pubmed: 32625205
Lancet. 2012 Aug 18;380(9842):651-9
pubmed: 22901886
Front Physiol. 2021 Jun 30;12:687381
pubmed: 34276407
Lancet Respir Med. 2015 May;3(5):355-66
pubmed: 25736990
Pharmacol Ther. 2021 Sep;225:107839
pubmed: 33774068
J Allergy Clin Immunol. 2007 Jun;119(6):1367-74
pubmed: 17481707
J Allergy Clin Immunol. 2017 Jan;139(1):93-103
pubmed: 27312821
J Thorac Dis. 2020 Oct;12(10):6090-6101
pubmed: 33209441
Cell Physiol Biochem. 2018;47(4):1482-1496
pubmed: 29940571
J Allergy Clin Immunol. 2014 Mar;133(3):729-38.e18
pubmed: 24238646
Clin Exp Allergy. 2016 Nov;46(11):1407-1415
pubmed: 27377155
Clin Exp Allergy. 2008 Jun;38(6):872-97
pubmed: 18498538
Pharmacol Ther. 2021 Sep;225:107847
pubmed: 33819560
J Allergy Clin Immunol. 2019 Apr;143(4):1287-1294
pubmed: 29928921
Nature. 2007 Jul 26;448(7152):470-3
pubmed: 17611496
Int Immunopharmacol. 2012 Feb;12(2):350-7
pubmed: 22210372
Histopathology. 2002 Apr;40(4):367-73
pubmed: 11943022
Clin Exp Allergy. 2013 Dec;43(12):1342-50
pubmed: 24261944
J Allergy Clin Immunol. 2013 Oct;132(4):933-41
pubmed: 23810766
Int J Biochem Cell Biol. 2002 Oct;34(10):1256-67
pubmed: 12127576
Clin Rev Allergy Immunol. 2019 Apr;56(2):219-233
pubmed: 30206782
Clin Exp Allergy. 2009 Jan;39(1):89-100
pubmed: 19055649
Clin Chest Med. 2012 Sep;33(3):559-70
pubmed: 22929102
Respir Res. 2015 Mar 18;16:39
pubmed: 25889697
J Allergy Clin Immunol. 2015 Jul;136(1):51-58.e10
pubmed: 25592985
Biochim Biophys Acta Mol Cell Res. 2021 Sep;1868(10):119083
pubmed: 34147561
Lancet. 2016 Oct 29;388(10056):2115-2127
pubmed: 27609408
Front Immunol. 2018 Nov 13;9:2601
pubmed: 30483263
PLoS One. 2013;8(1):e51268
pubmed: 23300949
Cells. 2021 Aug 06;10(8):
pubmed: 34440780
Cell Physiol Biochem. 2018;50(2):757-767
pubmed: 30308508
J Appl Physiol (1985). 1997 Dec;83(6):1814-21
pubmed: 9390950
Am J Respir Crit Care Med. 2015 Jul 15;192(2):164-71
pubmed: 25961111
Vaccines (Basel). 2022 Jun 19;10(6):
pubmed: 35746582
Am J Respir Crit Care Med. 2003 May 15;167(10):1360-8
pubmed: 12531777
Sci Immunol. 2020 Mar 27;5(45):
pubmed: 32220976
Am J Reprod Immunol. 2013 Jul;70(1):69-79
pubmed: 23495958
N Engl J Med. 2009 Mar 5;360(10):973-84
pubmed: 19264686
J Clin Invest. 2003 Oct;112(7):1029-36
pubmed: 14523040
J Asthma Allergy. 2022 Apr 18;15:487-504
pubmed: 35463205
Allergy. 2015 May;70(5):556-67
pubmed: 25683166
J Asthma Allergy. 2022 May 11;15:595-610
pubmed: 35592385
Genes Genomics. 2020 Dec;42(12):1399-1406
pubmed: 33040302
Signal Transduct Target Ther. 2021 Aug 4;6(1):291
pubmed: 34344870
Int J Prev Med. 2017 Aug 31;8:65
pubmed: 28966754
Respir Physiol. 2000 Jan;119(1):1-17
pubmed: 10701703
Eur Respir J. 2016 May;47(5):1568-71
pubmed: 26869673
Chest. 2021 May;159(5):1734-1746
pubmed: 33333058
Respiration. 2012;83(6):520-8
pubmed: 22236804
Am J Respir Crit Care Med. 2017 Jan 15;195(2):e4-e19
pubmed: 28084822
Mucosal Immunol. 2012 Nov;5(6):605-9
pubmed: 22910216
N Engl J Med. 2017 Sep 7;377(10):936-946
pubmed: 28877011
Am J Respir Crit Care Med. 1999 Sep;160(3):1001-8
pubmed: 10471631
Int Arch Allergy Immunol. 2022;183(7):714-725
pubmed: 35193134
Eur Respir J. 2019 Nov 14;54(5):
pubmed: 31391226
Lancet Respir Med. 2021 Nov;9(11):1299-1312
pubmed: 34256031
Am J Respir Crit Care Med. 2003 Mar 1;167(5):751-7
pubmed: 12468439
J Allergy Clin Immunol. 2014 Sep;134(3):671-678.e4
pubmed: 25171868
Nat Rev Immunol. 2015 Jan;15(1):57-65
pubmed: 25534623
Chest. 2002 Dec;122(6 Suppl):278S-284S
pubmed: 12475799
Am J Physiol Lung Cell Mol Physiol. 2010 Jun;298(6):L715-31
pubmed: 20363851
Eur Respir Rev. 2021 Jan 19;30(159):
pubmed: 33472957
Cell Tissue Res. 2017 Mar;367(3):551-569
pubmed: 28190087
J Allergy Clin Immunol. 2016 May;137(5):1413-1422.e12
pubmed: 27006248
Allergy Asthma Immunol Res. 2019 Sep;11(5):604-621
pubmed: 31332973
J Allergy Clin Immunol. 2014 Jun;133(6):1557-63.e5
pubmed: 24332216
J Asthma. 2014 Oct;51(8):863-9
pubmed: 24796648
J Allergy Clin Immunol. 2013 Sep;132(3):676-685.e13
pubmed: 23759184
Science. 2019 Mar 15;363(6432):
pubmed: 30872492
Eur Respir J. 2016 Jun;47(6):1855-7
pubmed: 26989102
Int J Immunopathol Pharmacol. 2012 Apr-Jun;25(2):475-84
pubmed: 22697079
Am J Respir Crit Care Med. 2022 May 1;205(9):1036-1045
pubmed: 35104436
Cells. 2022 Apr 20;11(9):
pubmed: 35563693
Sci Rep. 2023 Jun 17;13(1):9825
pubmed: 37330528
J Immunol. 2005 Jun 15;174(12):8183-90
pubmed: 15944327
Allergy. 2022 Dec;77(12):3538-3552
pubmed: 35950646
Chest. 2016 Oct;150(4):789-798
pubmed: 27056586
J Allergy Clin Immunol. 2001 Feb;107(2):295-301
pubmed: 11174196
Allergy. 2019 Jun;74(6):1102-1112
pubmed: 30667542
J Clin Immunol. 2013 Apr;33(3):595-604
pubmed: 23180361
Respirology. 2023 Aug;28(8):709-721
pubmed: 37222237
Immunol Cell Biol. 2007 Jul;85(5):348-56
pubmed: 17325694
Eur Respir J. 2021 Oct 21;58(4):
pubmed: 34675035
J Immunol Res. 2017;2017:3743048
pubmed: 29359169
Can Respir J. 2010 Jul-Aug;17(4):e85-93
pubmed: 20808979
Lancet. 2016 Jul 2;388(10039):31-44
pubmed: 27130691
J Allergy Clin Immunol. 2022 Feb;149(2):455-465
pubmed: 35125181
J Allergy Clin Immunol. 2012 Jan;129(1):104-11.e1-9
pubmed: 21975173