Knowledge-based, computerized, patient clinical decision support system for perioperative pain, nausea and constipation management: a clinical feasibility study.

Clinical decision support system Pain management Perioperative medicine Postoperative nausea and vomiting Postoperative pain

Journal

Journal of clinical monitoring and computing
ISSN: 1573-2614
Titre abrégé: J Clin Monit Comput
Pays: Netherlands
ID NLM: 9806357

Informations de publication

Date de publication:
12 Apr 2024
Historique:
received: 15 12 2023
accepted: 01 03 2024
medline: 13 4 2024
pubmed: 13 4 2024
entrez: 12 4 2024
Statut: aheadofprint

Résumé

Opioid administration is particularly challenging in the perioperative period. Computerized-based Clinical Decision Support Systems (CDSS) are a promising innovation that might improve perioperative pain control. We report the development and feasibility validation of a knowledge-based CDSS aiming at optimizing the management of perioperative pain, postoperative nausea and vomiting (PONV), and laxative medications. This novel CDSS uses patient adaptive testing through a smartphone display, literature-based rules, and individual medical prescriptions to produce direct medical advice for the patient user. Our objective was to test the feasibility of the clinical use of our CDSS in the perioperative setting. This was a prospective single arm, single center, cohort study conducted in Strasbourg University Hospital. The primary outcome was the agreement between the recommendation provided by the experimental device and the recommendation provided by study personnel who interpreted the same care algorithm (control). Thirty-seven patients were included in the study of which 30 (81%) used the experimental device. Agreement between these two care recommendations (computer driven vs. clinician driven) was observed in 51 out 54 uses of the device (94.2% [95% CI 85.9-98.4%]). The agreement level had a probability of 86.6% to exceed the 90% clinically relevant agreement threshold. The knowledge-based, patient CDSS we developed was feasible at providing recommendations for the treatment of pain, PONV and constipation in a perioperative clinical setting.Trial registration number & date The study protocol was registered in ClinicalTrial.gov before enrollment began (NCT05707247 on January 26th, 2023).

Identifiants

pubmed: 38609723
doi: 10.1007/s10877-024-01148-z
pii: 10.1007/s10877-024-01148-z
doi:

Banques de données

ClinicalTrials.gov
['NCT05707247']

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s).

Références

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Auteurs

Eric Noll (E)

Department of Anesthesiology, Intensive Care and Perioperative Medicine, Hautepierre Hospital, Strasbourg University Hospitals, Strasbourg, France. Eric.noll@chru-strasbourg.fr.

Melanie Noll-Burgin (M)

Department of Pharmacy, Groupe Hospitalier Saint Vincent, Strasbourg, France.

François Bonnomet (F)

Department of Orthopedic and Trauma Surgery, Hautepierre Hospital, Strasbourg University Hospitals, Strasbourg, France.

Aurelie Reiter-Schatz (A)

Department of Pharmacy, Hautepierre Hospital, Strasbourg University Hospitals, Strasbourg, France.

Benedicte Gourieux (B)

Department of Pharmacy, Hautepierre Hospital, Strasbourg University Hospitals, Strasbourg, France.

Elliott Bennett-Guerrero (E)

Department of Anesthesiology, Stony-Brook Medicine, Stony-Brook, NY, USA.

Thibaut Goetsch (T)

Department of Biostatistics, Strasbourg University Hospitals, Strasbourg, France.

Nicolas Meyer (N)

Department of Biostatistics, Strasbourg University Hospitals, Strasbourg, France.

Julien Pottecher (J)

Department of Anesthesiology and Intensive Care, Hautepierre Hospital, Strasbourg University Hospitals, Strasbourg, France.

Classifications MeSH