Paraaortic Extra-Adrenal Paraganglioma: Challenging Robotic Resection.
Journal
Annals of surgical oncology
ISSN: 1534-4681
Titre abrégé: Ann Surg Oncol
Pays: United States
ID NLM: 9420840
Informations de publication
Date de publication:
13 Apr 2024
13 Apr 2024
Historique:
received:
22
01
2024
accepted:
25
03
2024
medline:
14
4
2024
pubmed:
14
4
2024
entrez:
13
4
2024
Statut:
aheadofprint
Résumé
Up to 41% of intra- and extra-adrenal paragangliomas are linked to germline mutations with autosomal dominant transmission, which necessitates genetic testing for patients and their relatives. We present a multimedia article featuring a step-by-step video of a complex retroperitoneal resection, enriched with perioperative management insights. A 17-year-old female presented with episodes of hypertension, tachycardia, and diffuse diaphoresis. CT revealed a paraaortic mass adjacent to the left renal hilum later confirmed by a SPECT/CT with iodine-123 meta-iodobenzylguanidine. Robotic-assisted resection can be safe and effective for retroperitoneal malignant paragangliomas. However, management extends beyond surgery and requires cascade genetic testing to address familial risks. Because of the high probability of cancer associated with SDHB mutation, lifelong patient surveillance is imperative.
Sections du résumé
BACKGROUND
BACKGROUND
Up to 41% of intra- and extra-adrenal paragangliomas are linked to germline mutations with autosomal dominant transmission, which necessitates genetic testing for patients and their relatives.
METHODS
METHODS
We present a multimedia article featuring a step-by-step video of a complex retroperitoneal resection, enriched with perioperative management insights.
RESULTS
RESULTS
A 17-year-old female presented with episodes of hypertension, tachycardia, and diffuse diaphoresis. CT revealed a paraaortic mass adjacent to the left renal hilum later confirmed by a SPECT/CT with iodine-123 meta-iodobenzylguanidine.
CONCLUSIONS
CONCLUSIONS
Robotic-assisted resection can be safe and effective for retroperitoneal malignant paragangliomas. However, management extends beyond surgery and requires cascade genetic testing to address familial risks. Because of the high probability of cancer associated with SDHB mutation, lifelong patient surveillance is imperative.
Identifiants
pubmed: 38615151
doi: 10.1245/s10434-024-15267-z
pii: 10.1245/s10434-024-15267-z
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024. Society of Surgical Oncology.
Références
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