Fillers impacting follicles: the emerging complication of filler-induced alopecia.

alopecia autologous fat calcium hydroxylapatite dermal fillers filler filler‐induced alopecia hyaluronic acid

Journal

International journal of dermatology
ISSN: 1365-4632
Titre abrégé: Int J Dermatol
Pays: England
ID NLM: 0243704

Informations de publication

Date de publication:
14 Apr 2024
Historique:
revised: 16 03 2024
received: 15 01 2024
accepted: 19 03 2024
medline: 14 4 2024
pubmed: 14 4 2024
entrez: 14 4 2024
Statut: aheadofprint

Résumé

Filler-induced alopecia is a transient alopecia characterized by localized hair loss and often attributed to vascular compromise following dermal filler injections in facial regions. Although an uncommon phenomenon, the rising incidence of filler-induced alopecia underscores the importance of understanding and managing this condition. We performed an extensive PubMed review of articles reporting filler-induced alopecia and summarizing the implicated filler types, injection areas, hair loss patterns, symptom onset, course progression, treatments, and prognosis. Hyaluronic acid injections were the most implicated in filler-induced alopecia cases, with calcium hydroxylapatite and autologous fat less frequently associated. No cases involved other dermal filler types. Although recovery times varied depending on the treatment, hyaluronidase (HAase) injections rapidly restored near-normal hair density within 3-4 months. Minoxidil and platelet-rich plasma play a more minor role in restoring hair growth but may be used as adjuncts with HAase to facilitate hair growth. Finally, alternative interventions like intralesional triamcinolone, warm compresses, and nitroglycerin warrant exploration, given limited robust clinical data. Our study promotes awareness of filler-induced alopecia's rising incidence and offers practical insights and evidence-based recommendations for effective management. By equipping dermatologists with this knowledge, our aim is to improve patient outcomes and reduce adverse events in filler-based procedures.

Identifiants

pubmed: 38615331
doi: 10.1111/ijd.17169
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024 the International Society of Dermatology.

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Auteurs

Anika Pulumati (A)

University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.
Department of Dermatology and Cutaneous Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, FL, USA.

Yanci Algarin (Y)

Department of Dermatology and Cutaneous Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, FL, USA.
Eastern Virginia Medical School, Norfolk, VA, USA.

Dana Jaalouk (D)

Department of Dermatology and Cutaneous Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, FL, USA.
Florida State University College of Medicine, Tallahassee, FL, USA.

Steven Latta (S)

Herbert Wertheim College of Medicine, Miami, FL, USA.

Keyvan Nouri (K)

Department of Dermatology and Cutaneous Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, FL, USA.

Classifications MeSH