Long Term Survival Benefits of Different Conduits Used in Coronary Artery Bypass Graft Surgery- A Single Institutional Practice Over 20 Years.

CABG bilateral internal mammary artery coronary artery bypass graft long term outcome mortality multiple arterial graft survival benefits total arterial CABG

Journal

Journal of multidisciplinary healthcare
ISSN: 1178-2390
Titre abrégé: J Multidiscip Healthc
Pays: New Zealand
ID NLM: 101512691

Informations de publication

Date de publication:
2024
Historique:
received: 21 02 2024
accepted: 03 04 2024
medline: 15 4 2024
pubmed: 15 4 2024
entrez: 15 4 2024
Statut: epublish

Résumé

This study determined hazard factors and long-term survival rate of total arterial coronary artery bypass graft surgery over 20 years in an extensively large, population-based cohort. A total of 2979 patients who underwent isolated CABG from April 1999 to March 2020 were studied in 4 groups- Group-A (bilateral internal mammary artery ± radial artery), Group-B (single internal mammary artery + radial artery ± saphenous vein), Group-C (single internal mammary artery ± saphenous vein; no radial artery), and Group-D (radial artery ± saphenous vein; no internal mammary artery). The study endpoints analysed the correlation between the number and types of grafts with the survival time following isolated CABG surgery. The total arterial revascularization (Group A) group had an admirable mean long-term survival of ~19 years, compared to 18.6 years (Group B), 15.86 years (Group C), and 10.99 years (Group D). A Kaplan-Meier curve demonstrated confidence interval (CI) for study groups- (95% CI 18.33-19.94), (95% CI 18.14-19.06), (95% CI 15.40-16.32), and (95% CI 9.61-12.38) in Group A, B, C, D respectively. In the Holm-Sidak method analysis, significant associations existed between the number of arterial grafts and the long-term outcome. A statistically significant (P≤0.05) long-term survival advantage for arterial grafting was demonstrated, especially total arterial revascularisation over all other combinations except single internal mammary artery + radial artery grafting. In this series, over 20 years, total arterial CABG use has excellent long-term survival, achieving complete myocardial revascularisation. There is no significant difference between the BIMA group and SIMA with radial artery. However, there is a reduced survival with decreased use of arterial conduits.

Identifiants

pubmed: 38617079
doi: 10.2147/JMDH.S461567
pii: 461567
pmc: PMC11011645
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1505-1512

Informations de copyright

© 2024 Momin et al.

Déclaration de conflit d'intérêts

The authors report no conflicts of interest in this work.

Auteurs

Aziz Momin (A)

Department of Cardiac Surgery, St George's University Hospitals NHS Foundation Trust, London, UK.

Redoy Ranjan (R)

Department of Cardiac Surgery, St George's University Hospitals NHS Foundation Trust, London, UK.
Department of Cardiac Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.

Oswaldo Valencia (O)

Department of Cardiac Surgery, St George's University Hospitals NHS Foundation Trust, London, UK.

Adam Jacques (A)

Department of Cardiology, Ashford and St Peter's Hospitals NHS Foundation Trust, London, UK.

Pitt Lim (P)

Department of Cardiology, St George's University Hospitals NHS Foundation Trust, London, UK.

David Fluck (D)

Department of Cardiology, Ashford and St Peter's Hospitals NHS Foundation Trust, London, UK.

Tuan P Chua (TP)

Department of Cardiology, Royal Surrey NHS Foundation Trust, London, UK.

Venkatachalam Chandrasekaran (V)

Department of Cardiac Surgery, St George's University Hospitals NHS Foundation Trust, London, UK.

Classifications MeSH