Routine utilization of machine perfusion in liver transplantation: Ready for prime time?

Hypothermic oxygenated perfusion Liver transplantation Machine perfusion Normothermic machine perfusion Viability assessment

Journal

World journal of gastroenterology
ISSN: 2219-2840
Titre abrégé: World J Gastroenterol
Pays: United States
ID NLM: 100883448

Informations de publication

Date de publication:
21 Mar 2024
Historique:
received: 03 01 2024
revised: 30 01 2024
accepted: 28 02 2024
medline: 15 4 2024
pubmed: 15 4 2024
entrez: 15 4 2024
Statut: ppublish

Résumé

The last decade has been notable for increasing high-quality research and dramatic improvement in outcomes with dynamic liver preservation. Robust evidence from numerous randomized controlled trials has been pooled by meta-analyses, providing the highest available evidence on the protective effect of machine perfusion (MP) over static cold storage in liver transplantation (LT). Based on a protective effect with less complications and improved graft survival, the field has seen a paradigm shift in organ preservation. This editorial focuses on the role of MP in LT and how it could become the new "gold standard". Strong collaborative efforts are needed to explore its effects on long-term outcomes.

Identifiants

pubmed: 38617447
doi: 10.3748/wjg.v30.i11.1488
pmc: PMC11008417
doi:

Types de publication

Editorial

Langues

eng

Sous-ensembles de citation

IM

Pagination

1488-1493

Informations de copyright

©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict-of-interest statement: All authors declare no conflict of interest.

Auteurs

Alessandro Parente (A)

Department of Surgery, Division of Transplantation, University of Alberta Hospital, Edmonton T6G 2B7, Canada. aleparen@gmail.com.

Keyue Sun (K)

Immunity and Inflammation, Lerner Research Institute, Cleveland, OH 44195, United States.

Philipp Dutkowski (P)

Swiss Hepato-Pancreato-Biliary Center, Department of Visceral and Transplantation Surgery, University Hospital Zurich, Zurich 8091, Switzerland.

Am James Shapiro (AJ)

Department of Surgery, Division of Transplantation, University of Alberta Hospital, Edmonton T6G 2B7, Canada.

Andrea Schlegel (A)

Immunity and Inflammation, Digestive Disease and Surgery Institute, Cleveland, OH 44195, United States.

Classifications MeSH