Solubility, Thermodynamic Parameters, and Dissolution Properties of 17-α Hydroxyprogesterone in 13 Pure Solvents.


Journal

ACS omega
ISSN: 2470-1343
Titre abrégé: ACS Omega
Pays: United States
ID NLM: 101691658

Informations de publication

Date de publication:
09 Apr 2024
Historique:
received: 12 12 2023
revised: 08 03 2024
accepted: 13 03 2024
medline: 15 4 2024
pubmed: 15 4 2024
entrez: 15 4 2024
Statut: epublish

Résumé

The static gravimetric method was used to measure the solubility of 17-α hydroxyprogesterone (OHP) in 13 pure solvents ranging from 278.15 to 323.15 K. The results indicate that the experimental solubility of OHP increases with increasing temperature. The experimental solubility data were correlated by the selected van't Hoff model, λ

Identifiants

pubmed: 38617637
doi: 10.1021/acsomega.3c09922
pmc: PMC11007714
doi:

Types de publication

Journal Article

Langues

eng

Pagination

16106-16117

Informations de copyright

© 2024 The Authors. Published by American Chemical Society.

Déclaration de conflit d'intérêts

The authors declare no competing financial interest.

Auteurs

Qi Zhao (Q)

School of Pharmaceutical Sciences, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250014, P. R. China.

Yinhu Pan (Y)

School of Material Science and Engineering, Shandong Jianzhu University, Jinan 250101, P. R. China.

Yankai Xiong (Y)

Shandong Provincial Center for Solid Waste and Hazardous Chemical Pollution Control, Jinan 250014, P. R. China.

Ping Xu (P)

School of Pharmaceutical Sciences, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250014, P. R. China.

Qianyun Sun (Q)

Shandong Institute of Metrology, Jinan 250014, P. R. China.

Hemei Yin (H)

School of Pharmaceutical Sciences, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250014, P. R. China.

Fumin Xue (F)

School of Pharmaceutical Sciences, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250014, P. R. China.

Classifications MeSH