Effects of Sodium-Glucose Cotransporter 2 Inhibitors on Cause-Specific Cardiovascular Death in Patients with CKD: A Meta-Analysis of CKD Progression Trials.


Journal

Clinical journal of the American Society of Nephrology : CJASN
ISSN: 1555-905X
Titre abrégé: Clin J Am Soc Nephrol
Pays: United States
ID NLM: 101271570

Informations de publication

Date de publication:
16 Apr 2024
Historique:
pubmed: 16 4 2024
medline: 16 4 2024
entrez: 16 4 2024
Statut: aheadofprint

Résumé

Clinical Trial registry name and registration number: ClinicalTrials.gov Identifiers: NCT02065791 (CREDENCE), NCT03036150 (DAPA-CKD), NCT03594110 (EMPA-KIDNEY).

Identifiants

pubmed: 38622766
doi: 10.2215/CJN.0000000000000470
pii: 01277230-990000000-00370
doi:

Banques de données

ClinicalTrials.gov
['NCT03036150', 'NCT03594110', 'NCT02065791']

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024 by the American Society of Nephrology.

Références

Nuffield Department of Population Health Renal Studies Group, SGLT2 inhibitor Meta-Analysis Cardio-Renal Trialists' Consortium. Impact of diabetes on the effects of sodium glucose co-transporter-2 inhibitors on kidney outcomes: collaborative meta-analysis of large placebo-controlled trials. Lancet. 2022;400(10365):1788–1801. doi: 10.1016/S0140-6736(22)02074-8
doi: 10.1016/S0140-6736(22)02074-8
Perkovic V, Jardine MJ, Neal B, et al.; CREDENCE Trial Investigators. Canagliflozin and renal outcomes in type 2 diabetes and nephropathy. New Engl J Med. 2019;380(24):2295–2306. doi: 10.1056/NEJMoa1811744
doi: 10.1056/NEJMoa1811744
Heerspink HJ, Stefánsson BV, Correa-Rotter R, et al.; DAPA-CKD Trial Committees and Investigators. Dapagliflozin in patients with chronic kidney disease. New Engl J Med. 2020;383(15):1436–1446. doi: 10.1056/NEJMoa2024816
doi: 10.1056/NEJMoa2024816
Herrington WG, Staplin N, Wanner C, et al.; The EMPA-KIDNEY Collaborative Group. Empagliflozin in patients with chronic kidney disease. New Engl J Med. 2023;388(2):117–127. doi: 10.1056/NEJMoa2204233
doi: 10.1056/NEJMoa2204233
Heerspink HJL, Sjöström CD, Jongs N, et al.; DAPA-CKD Trial Committees and Investigators. Effects of dapagliflozin on mortality in patients with chronic kidney disease: a pre-specified analysis from the DAPA-CKD randomized controlled trial. Eur Heart J. 2021;42(13):1216–1227. doi: 10.1093/eurheartj/ehab094
doi: 10.1093/eurheartj/ehab094
Jankowski J, Floege J, Fliser D, Böhm M, Marx N. Cardiovascular disease in chronic kidney disease: pathophysiological insights and therapeutic options. Circulation. 2021;143(11):1157–1172. doi: 10.1161/CIRCULATIONAHA.120.050686
doi: 10.1161/CIRCULATIONAHA.120.050686

Auteurs

Robert A Fletcher (RA)

The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia.

William G Herrington (WG)

Medical Research Council Population Health Research Unit at the University of Oxford, Nuffield Department of Population Health (NDPH), University of Oxford, Oxford, United Kingdom.
Clinical Trial Service Unit and Epidemiologic Studies Unit (CTSU), NDPH, University of Oxford, Oxford, United Kingdom.
Oxford Kidney Unit, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.

Rajiv Agarwal (R)

Indiana University School of Medicine and VA Medical Center, Indianapolis, Indiana.

Kaitlin J Mayne (KJ)

Medical Research Council Population Health Research Unit at the University of Oxford, Nuffield Department of Population Health (NDPH), University of Oxford, Oxford, United Kingdom.
School of Cardiovascular and Metabolic Health, College of Medical and Veterinary Life Sciences, University of Glasgow, Glasgow, United Kingdom.

Clare Arnott (C)

The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia.
Department of Cardiology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.

Meg J Jardine (MJ)

NHMRC Clinical Trials Centre, University of Sydney, New South Wales, Australia.
Department of Renal Medicine, Concord Repatriation General Hospital, Sydney, New South Wales, Australia.

Kenneth W Mahaffey (KW)

Department of Medicine, Stanford Center for Clinical Research, Stanford University School of Medicine, Stanford, California.

Vlado Perkovic (V)

The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia.
Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia.

Natalie Staplin (N)

Medical Research Council Population Health Research Unit at the University of Oxford, Nuffield Department of Population Health (NDPH), University of Oxford, Oxford, United Kingdom.
Clinical Trial Service Unit and Epidemiologic Studies Unit (CTSU), NDPH, University of Oxford, Oxford, United Kingdom.

David C Wheeler (DC)

The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia.
Department of Renal Medicine, University College London, London, United Kingdom.

Glenn M Chertow (GM)

Departments of Medicine, Epidemiology and Population Health, and Health Policy, Stanford University School of Medicine, Stanford, California.

Hiddo J L Heerspink (HJL)

The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia.
Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Brendon L Neuen (BL)

The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia.
Department of Renal Medicine, Royal North Shore Hospital, Sydney, New South Wales, Australia.

Classifications MeSH