Effect of the Communities that HEAL intervention on receipt of behavioral therapies for opioid use disorder: A cluster randomized wait-list controlled trial.

Behavioral health Community intervention Medicaid Opioids Overdose Retention

Journal

Drug and alcohol dependence
ISSN: 1879-0046
Titre abrégé: Drug Alcohol Depend
Pays: Ireland
ID NLM: 7513587

Informations de publication

Date de publication:
05 Apr 2024
Historique:
received: 29 01 2024
revised: 28 03 2024
accepted: 31 03 2024
medline: 17 4 2024
pubmed: 17 4 2024
entrez: 16 4 2024
Statut: aheadofprint

Résumé

The U.S. opioid overdose crisis persists. Outpatient behavioral health services (BHS) are essential components of a comprehensive response to opioid use disorder and overdose fatalities. The Helping to End Addiction Long-Term® (HEALing) Communities Study developed the Communities That HEAL (CTH) intervention to reduce opioid overdose deaths in 67 communities in Kentucky, Ohio, New York, and Massachusetts through the implementation of evidence-based practices (EBPs), including BHS. This paper compares the rate of individuals receiving outpatient BHS in Wave 1 intervention communities (n = 34) to waitlisted Wave 2 communities (n = 33). Medicaid data included individuals ≥18 years of age receiving any of five BHS categories: intensive outpatient, outpatient, case management, peer support, and case management or peer support. Negative binomial regression models estimated the rate of receiving each BHS for Wave 1 and Wave 2. Effect modification analyses evaluated changes in the effect of the CTH intervention between Wave 1 and Wave 2 by research site, rurality, age, sex, and race/ethnicity. No significant differences were detected between intervention and waitlisted communities in the rate of individuals receiving any of the five BHS categories. None of the interaction effects used to test the effect modification were significant. Several factors should be considered when interpreting results-no significant intervention effects were observed through Medicaid claims data, the best available data source but limited in terms of capturing individuals reached by the intervention. Also, the 12-month evaluation window may have been too brief to see improved outcomes considering the time required to stand-up BHS. Clinical Trials.gov http://www. gov: Identifier: NCT04111939.

Sections du résumé

BACKGROUND BACKGROUND
The U.S. opioid overdose crisis persists. Outpatient behavioral health services (BHS) are essential components of a comprehensive response to opioid use disorder and overdose fatalities. The Helping to End Addiction Long-Term® (HEALing) Communities Study developed the Communities That HEAL (CTH) intervention to reduce opioid overdose deaths in 67 communities in Kentucky, Ohio, New York, and Massachusetts through the implementation of evidence-based practices (EBPs), including BHS. This paper compares the rate of individuals receiving outpatient BHS in Wave 1 intervention communities (n = 34) to waitlisted Wave 2 communities (n = 33).
METHODS METHODS
Medicaid data included individuals ≥18 years of age receiving any of five BHS categories: intensive outpatient, outpatient, case management, peer support, and case management or peer support. Negative binomial regression models estimated the rate of receiving each BHS for Wave 1 and Wave 2. Effect modification analyses evaluated changes in the effect of the CTH intervention between Wave 1 and Wave 2 by research site, rurality, age, sex, and race/ethnicity.
RESULTS RESULTS
No significant differences were detected between intervention and waitlisted communities in the rate of individuals receiving any of the five BHS categories. None of the interaction effects used to test the effect modification were significant.
CONCLUSIONS CONCLUSIONS
Several factors should be considered when interpreting results-no significant intervention effects were observed through Medicaid claims data, the best available data source but limited in terms of capturing individuals reached by the intervention. Also, the 12-month evaluation window may have been too brief to see improved outcomes considering the time required to stand-up BHS.
TRIAL REGISTRATION BACKGROUND
Clinical Trials.gov http://www.
CLINICALTRIALS RESULTS
gov: Identifier: NCT04111939.

Identifiants

pubmed: 38626553
pii: S0376-8716(24)00207-2
doi: 10.1016/j.drugalcdep.2024.111286
pii:
doi:

Banques de données

ClinicalTrials.gov
['NCT04111939']

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

111286

Informations de copyright

Copyright © 2024. Published by Elsevier B.V.

Déclaration de conflit d'intérêts

Declaration of Competing Interest In last three years, MRL has served as a scientific consultant for treatments in development for substance use disorders to Journey Colab, Titan, Braeburn, and Berkshire Biomedical. RDW has consulted to Alkermes.

Auteurs

LaShawn Glasgow (L)

RTI International, Research Triangle Park, NC, USA. Electronic address: lglasgow@rti.org.

Christian Douglas (C)

RTI International, Research Triangle Park, NC, USA.

Joel G Sprunger (JG)

University of Cincinnati College of Medicine, University of Cincinnati Center for Addiction Research, Cincinnati, OH, USA.

Aimee N C Campbell (ANC)

Columbia University Irving Medical Center, Department of Psychiatry, New York, NY, USA.

Redonna Chandler (R)

National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD, USA.

Anindita Dasgupta (A)

Columbia University Irving Medical Center, Department of Psychiatry, New York, NY, USA.

JaNae Holloway (J)

RTI International, Research Triangle Park, NC, USA.

Katherine R Marks (KR)

Kentucky Department for Behavioral Health, Developmental and Intellectual Disabilities, Frankfort, KY, USA.

Sara M Roberts (SM)

Case Western Reserve University School of Medicine, Cleveland, OH, USA.

Linda Sprague Martinez (LS)

Boston University School of Social Work, Boston, MA, USA.

Katherine Thompson (K)

University of Kentucky, Dr. Bing Zhang Department of Statistics, Lexington, KY, USA.

Roger D Weiss (RD)

McLean Hospital, Harvard Medical School, Belmont, MA, USA.

Arnie Aldridge (A)

RTI International, Research Triangle Park, NC, USA.

Kat Asman (K)

RTI International, Research Triangle Park, NC, USA.

Carolina Barbosa (C)

RTI International, Research Triangle Park, NC, USA.

Derek Blevins (D)

Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.

Deborah Chassler (D)

Boston University School of Social Work, Boston, MA, USA.

Lindsay Cogan (L)

New York State Department of Health, Office of Quality and Patient Safety, New York, NY, USA.

Laura Fanucchi (L)

University of Kentucky College of Medicine, Lexington, KY, USA.

Megan E Hall (ME)

RTI International, Research Triangle Park, NC, USA.

Timothy Hunt (T)

Columbia University School of Social Work, New York, NY, USA.

Elizabeth Jadovich (E)

Boston Medical Center, Boston, MA, USA.

Frances R Levin (FR)

Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.

Patricia Lincourt (P)

New York State Office of Addiction Services and Supports, Albany, NY, USA.

Michelle R Lofwall (MR)

University of Kentucky College of Medicine, Lexington, KY, USA.

Vanessa Loukas (V)

Boston Medical Center, Boston, MA, USA.

Ann Scheck McAlearney (AS)

Ohio State University College of Medicine, Columbus, OH, USA.

Edward Nunes (E)

Columbia University Irving Medical Center, Department of Psychiatry, New York, NY, USA.

Emmanuel Oga (E)

RTI International, Research Triangle Park, NC, USA.

Devin Oller (D)

University of Kentucky College of Medicine, Lexington, KY, USA.

Maria Rudorf (M)

Boston Medical Center, Boston, MA, USA.

Ann Marie Sullivan (AM)

New York State Office of Mental Health, USA.

Jeffery Talbert (J)

University of Kentucky College of Medicine, Lexington, KY, USA.

Angela Taylor (A)

University of Kentucky College of Medicine, Lexington, KY, USA.

Julie Teater (J)

Ohio State University College of Medicine, Columbus, OH, USA.

Nathan Vandergrift (N)

RTI International, Research Triangle Park, NC, USA.

Kristin Woodlock (K)

Woodlock & Associates, USA.

Gary A Zarkin (GA)

RTI International, Research Triangle Park, NC, USA.

Bridget Freisthler (B)

Ohio State University College of Social Work, Columbus, OH, USA.

Jeffrey H Samet (JH)

Boston University and Boston Medical Center, Boston, MA, USA.

Sharon L Walsh (SL)

University of Kentucky College of Medicine, Lexington, KY, USA.

Nabila El-Bassel (N)

Columbia University School of Social Work, New York, NY, USA.

Classifications MeSH