Orthotopic Robot-assisted Kidney Transplantation: Surgical Technique and Preliminary Results.

Kidney transplantation Orthotopic kidney transplantation Robot-assisted surgery Robotic surgery Transplantation

Journal

European urology
ISSN: 1873-7560
Titre abrégé: Eur Urol
Pays: Switzerland
ID NLM: 7512719

Informations de publication

Date de publication:
15 Apr 2024
Historique:
received: 20 01 2024
revised: 05 03 2024
accepted: 28 03 2024
medline: 17 4 2024
pubmed: 17 4 2024
entrez: 16 4 2024
Statut: aheadofprint

Résumé

Orthotopic kidney transplantation (KT) has been proposed as an option for patients ineligible for heterotopic KT. In this scenario, orthotopic robot-assisted KT (oRAKT) represents a novel, minimally invasive alternative to the open approach. Here we describe the largest oRAKT series of patients, with a focus on the surgical technique, perioperative surgical outcomes, and functional results. We queried prospectively maintained databases from three referral centers to identify patients who underwent oRAKT and evaluated surgical and functional outcomes. Overall, 16 oRAKT procedures were performed between January 2020 and August 2023. These involved four donors after cardiovascular death, five donors after brain death, and seven living donors. All oRAKT procedures were carried out in the left renal fossa. The indication for oRAKT was extensive calcification of the external iliac vessels (100%), frequently associated with prior KT (31%). The median operative time was 295 min (interquartile range [IQR] 268-360) and the median rewarming time 48 min (IQR 40-54). Conversion to open surgery occurred in two cases (12%), and delayed graft function was observed in two cases (12%). Postoperative complications occurred in 11 patients (69%) and three (18%) experienced Clavien-Dindo grade >II complications. At median follow-up of 9 mo (IQR 7-17), 14 patients had a functioning graft and median creatinine of 1.49 mg/dl (IQR 1.36-1.72). Although oRAKT is a challenging procedure, it represents a feasible option for individuals ineligible for heterotopic KT and yields favorable perioperative and mid-term functional outcomes. We evaluated outcomes of orthotopic robot-assisted kidney transplantation (KT), in which the native kidney is removed and the donor kidney is transplanted into its place, in patients who are not eligible for heterotopic KT, in which the native kidney is left in place and the donor kidney is transplanted into a new location. We found that robot-assisted surgery is a safe and feasible alternative to traditional open surgery for orthotopic KT.

Sections du résumé

BACKGROUND AND OBJECTIVE OBJECTIVE
Orthotopic kidney transplantation (KT) has been proposed as an option for patients ineligible for heterotopic KT. In this scenario, orthotopic robot-assisted KT (oRAKT) represents a novel, minimally invasive alternative to the open approach. Here we describe the largest oRAKT series of patients, with a focus on the surgical technique, perioperative surgical outcomes, and functional results.
METHODS METHODS
We queried prospectively maintained databases from three referral centers to identify patients who underwent oRAKT and evaluated surgical and functional outcomes.
KEY FINDINGS AND LIMITATIONS UNASSIGNED
Overall, 16 oRAKT procedures were performed between January 2020 and August 2023. These involved four donors after cardiovascular death, five donors after brain death, and seven living donors. All oRAKT procedures were carried out in the left renal fossa. The indication for oRAKT was extensive calcification of the external iliac vessels (100%), frequently associated with prior KT (31%). The median operative time was 295 min (interquartile range [IQR] 268-360) and the median rewarming time 48 min (IQR 40-54). Conversion to open surgery occurred in two cases (12%), and delayed graft function was observed in two cases (12%). Postoperative complications occurred in 11 patients (69%) and three (18%) experienced Clavien-Dindo grade >II complications. At median follow-up of 9 mo (IQR 7-17), 14 patients had a functioning graft and median creatinine of 1.49 mg/dl (IQR 1.36-1.72).
CONCLUSIONS AND CLINICAL IMPLICATIONS CONCLUSIONS
Although oRAKT is a challenging procedure, it represents a feasible option for individuals ineligible for heterotopic KT and yields favorable perioperative and mid-term functional outcomes.
PATIENT SUMMARY RESULTS
We evaluated outcomes of orthotopic robot-assisted kidney transplantation (KT), in which the native kidney is removed and the donor kidney is transplanted into its place, in patients who are not eligible for heterotopic KT, in which the native kidney is left in place and the donor kidney is transplanted into a new location. We found that robot-assisted surgery is a safe and feasible alternative to traditional open surgery for orthotopic KT.

Identifiants

pubmed: 38627151
pii: S0302-2838(24)02265-6
doi: 10.1016/j.eururo.2024.03.037
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024 European Association of Urology. Published by Elsevier B.V. All rights reserved.

Auteurs

Francesc Vigués (F)

Department of Urology, Hospital Universitari de Bellvitge, Universitat de Barcelona, L'Hospitalet de Llobregat, Spain.

Begoña Etcheverry (B)

Department of Urology, Hospital Universitari de Bellvitge, Universitat de Barcelona, L'Hospitalet de Llobregat, Spain.

José I Perez Reggeti (JI)

Department of Urology, Hospital Universitari de Bellvitge, Universitat de Barcelona, L'Hospitalet de Llobregat, Spain.

Josep Maria Gaya (JM)

Department of Urology, Fundació Puigvert, Universitat Autonoma de Barcelona, Barcelona, Spain.

Angelo Territo (A)

Department of Urology, Fundació Puigvert, Universitat Autonoma de Barcelona, Barcelona, Spain.

Andrea Gallioli (A)

Department of Urology, Fundació Puigvert, Universitat Autonoma de Barcelona, Barcelona, Spain.

Camille Berquin (C)

Department of Urology, Fundació Puigvert, Universitat Autonoma de Barcelona, Barcelona, Spain; Department of Urology, University Hospital Ghent, Ghent, Belgium.

Giuseppe Basile (G)

Department of Urology, Fundació Puigvert, Universitat Autonoma de Barcelona, Barcelona, Spain; Department of Urology, Division of Experimental Oncology, Urological Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy.

José F Suárez (JF)

Department of Urology, Hospital Universitari de Bellvitge, Universitat de Barcelona, L'Hospitalet de Llobregat, Spain.

Maria Fiol (M)

Department of Urology, Hospital Universitari de Bellvitge, Universitat de Barcelona, L'Hospitalet de Llobregat, Spain.

Oscar Buisan (O)

Department of Urology, Hospital Universitari de Bellvitge, Universitat de Barcelona, L'Hospitalet de Llobregat, Spain.

Lluís Riera (L)

Department of Urology, Hospital Universitari de Bellvitge, Universitat de Barcelona, L'Hospitalet de Llobregat, Spain.

Thomas Prudhomme (T)

Department of Urology and Renal Transplantation, University Hospital of Rangueil, Toulouse, France.

Nicolas Doumerc (N)

Department of Urology and Renal Transplantation, University Hospital of Rangueil, Toulouse, France.

Alessio Pecoraro (A)

Department of Urology, Fundació Puigvert, Universitat Autonoma de Barcelona, Barcelona, Spain; Unit of Urological Minimally Invasive, Robotic Surgery and Kidney Transplantation, Careggi Hospital, University of Florence, Florence, Italy. Electronic address: alessio.pecoraro10@gmail.com.

Alberto Breda (A)

Department of Urology, Fundació Puigvert, Universitat Autonoma de Barcelona, Barcelona, Spain.

Classifications MeSH