CT Scan Data Analysis in Malformations of Cortical Development.

Brain malformations CT scan Computed tomography Cortical development Malformations of cortical development Radiations

Journal

Methods in molecular biology (Clifton, N.J.)
ISSN: 1940-6029
Titre abrégé: Methods Mol Biol
Pays: United States
ID NLM: 9214969

Informations de publication

Date de publication:
2024
Historique:
medline: 17 4 2024
pubmed: 17 4 2024
entrez: 17 4 2024
Statut: ppublish

Résumé

Malformations of cortical development (MCDs) are a diverse group of disorders that result from abnormal neuronal migration, proliferation, and differentiation during brain development. Head computed tomography (CT) has limited use in the diagnosis of MCDs and should be reserved for selected cases with specific indications or when magnetic resonance imaging is not available or contraindicated. CT can detect brain calcifications associated with MCDs, thus helping in the differential diagnosis between acquired and genetic MCDs or in the identification of different genetic patterns. Moreover, CT can provide high-resolution images of the skull and bones, thus identifying associated malformations, such as craniosynostosis, inner and middle ear malformations, and vertebral anomalies. In this chapter, we review the CT scan technique, data analysis, and indications in the investigation of MCDs.

Identifiants

pubmed: 38630236
doi: 10.1007/978-1-0716-3810-1_22
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

271-280

Informations de copyright

© 2024. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.

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Auteurs

Marcello Scala (M)

Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy.
UOC Genetica Medica, IRCCS Giannina Gaslini, Genoa, Italy.

Mariasavina Severino (M)

Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy.
Neuroradiology Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.

Classifications MeSH