Stepwise activation of a metabotropic glutamate receptor.


Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
17 Apr 2024
Historique:
received: 28 08 2023
accepted: 15 03 2024
medline: 18 4 2024
pubmed: 18 4 2024
entrez: 17 4 2024
Statut: aheadofprint

Résumé

Metabotropic glutamate receptors belong to a family of G protein-coupled receptors that are obligate dimers and possess a large extracellular ligand-binding domain that is linked via a cysteine-rich domain to their 7-transmembrane domain

Identifiants

pubmed: 38632403
doi: 10.1038/s41586-024-07327-x
pii: 10.1038/s41586-024-07327-x
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s), under exclusive licence to Springer Nature Limited.

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Auteurs

Kaavya Krishna Kumar (K)

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA. kaavyak@stanford.edu.

Haoqing Wang (H)

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.
Sarafan ChEM-H, Stanford University, Stanford, CA, USA.

Chris Habrian (C)

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.

Naomi R Latorraca (NR)

Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.

Jun Xu (J)

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.

Evan S O'Brien (ES)

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.

Chensong Zhang (C)

Division of CryoEM and Bioimaging, Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA, USA.

Elizabeth Montabana (E)

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.

Antoine Koehl (A)

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.
Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA, USA.

Susan Marqusee (S)

Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.
QB3 Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, CA, USA.
Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA.

Ehud Y Isacoff (EY)

Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.
Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, USA.

Brian K Kobilka (BK)

Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA. kobilka@stanford.edu.

Classifications MeSH