Promiscuous G-protein activation by the calcium-sensing receptor.

Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
17 Apr 2024
Historique:
received: 27 06 2023
accepted: 18 03 2024
medline: 18 4 2024
pubmed: 18 4 2024
entrez: 17 4 2024
Statut: aheadofprint

Résumé

The human calcium-sensing receptor (CaSR) detects fluctuations in the extracellular Ca

Identifiants

DOI: 10.1038/s41586-024-07331-1 PMID: 38632411
pubmed: 38632411
doi: 10.1038/s41586-024-07331-1
pii: 10.1038/s41586-024-07331-1
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s), under exclusive licence to Springer Nature Limited.

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Auteurs

Hao Zuo (H)

Department of Molecular Pharmacology and Therapeutics, Columbia University, New York, NY, USA.
ORCID: 0000-0002-8812-7385

Jinseo Park (J)

Department of Molecular Pharmacology and Therapeutics, Columbia University, New York, NY, USA.

Aurel Frangaj (A)

Department of Molecular Pharmacology and Therapeutics, Columbia University, New York, NY, USA.
ORCID: 0000-0002-4990-513X

Jianxiang Ye (J)

Department of Physiology and Cellular Biophysics, Columbia University, New York, NY, USA.
ORCID: 0009-0004-2353-2162

Guanqi Lu (G)

Department of Biological Sciences, Columbia University, New York, NY, USA.

Jamie J Manning (JJ)

Department of Psychiatry, Columbia University, New York, NY, USA.
Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA.
ORCID: 0000-0002-6945-2254

Wesley B Asher (WB)

Department of Psychiatry, Columbia University, New York, NY, USA.
Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA.
ORCID: 0000-0001-7437-218X

Zhengyuan Lu (Z)

Department of Biological Sciences, Columbia University, New York, NY, USA.
ORCID: 0000-0002-4262-1193

Guo-Bin Hu (GB)

Laboratory for BioMolecular Structure, Brookhaven National Laboratory, Upton, NY, USA.

Liguo Wang (L)

Laboratory for BioMolecular Structure, Brookhaven National Laboratory, Upton, NY, USA.

Joshua Mendez (J)

National Center for Cryo-EM Access and Training, Simons Electron Microscopy Center, New York Structural Biology Center, New York, NY, USA.
ORCID: 0000-0002-3317-5654

Edward Eng (E)

National Center for Cryo-EM Access and Training, Simons Electron Microscopy Center, New York Structural Biology Center, New York, NY, USA.
ORCID: 0000-0002-8014-7269

Zhening Zhang (Z)

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.

Xin Lin (X)

Department of Psychiatry, Columbia University, New York, NY, USA.
Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA.

Robert Grassucci (R)

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.

Wayne A Hendrickson (WA)

Department of Physiology and Cellular Biophysics, Columbia University, New York, NY, USA.
Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.
ORCID: 0000-0003-1412-5747

Oliver B Clarke (OB)

Department of Physiology and Cellular Biophysics, Columbia University, New York, NY, USA.
Department of Anesthesiology, Columbia University, New York, NY, USA.
Irving Institute for Clinical and Translational Research, Columbia University, New York, NY, USA.

Jonathan A Javitch (JA)

Department of Molecular Pharmacology and Therapeutics, Columbia University, New York, NY, USA. Jonathan.Javitch@nyspi.columbia.edu.
Department of Physiology and Cellular Biophysics, Columbia University, New York, NY, USA. Jonathan.Javitch@nyspi.columbia.edu.
Department of Psychiatry, Columbia University, New York, NY, USA. Jonathan.Javitch@nyspi.columbia.edu.
Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY, USA. Jonathan.Javitch@nyspi.columbia.edu.
ORCID: 0000-0001-7395-2967

Arthur D Conigrave (AD)

School of Life & Environmental Sciences, Charles Perkins Centre, University of Sydney, Camperdown, New South Wales, Australia. arthur.conigrave@sydney.edu.au.
ORCID: 0000-0002-7232-3891

Qing R Fan (QR)

Department of Molecular Pharmacology and Therapeutics, Columbia University, New York, NY, USA. qf13@cumc.columbia.edu.
Department of Pathology and Cell Biology, Columbia University, New York, NY, USA. qf13@cumc.columbia.edu.
ORCID: 0000-0002-9330-0963

Classifications MeSH