Omega-3 and omega-6 polyunsaturated fatty acids and their potential therapeutic role in protozoan infections.

mechanism of action omega polyunsaturated fatty acids parasitic infections prevention supportive therapy

Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2024
Historique:
received: 16 11 2023
accepted: 21 03 2024
medline: 18 4 2024
pubmed: 18 4 2024
entrez: 18 4 2024
Statut: epublish

Résumé

Protozoa exert a serious global threat of growing concern to human, and animal, and there is a need for the advancement of novel therapeutic strategies to effectively treat or mitigate the impact of associated diseases. Omega polyunsaturated fatty acids (ω-PUFAs), including Omega-3 (ω-3) and omega-6 (ω-6), are constituents derived from various natural sources, have gained significant attention for their therapeutic role in parasitic infections and a variety of essential structural and regulatory functions in animals and humans. Both ω-3 and ω-6 decrease the growth and survival rate of parasites through metabolized anti-inflammatory mediators, such as lipoxins, resolvins, and protectins, and have both

Identifiants

pubmed: 38633251
doi: 10.3389/fimmu.2024.1339470
pmc: PMC11022163
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1339470

Informations de copyright

Copyright © 2024 Rahman, Weng, Qadeer, Nawaz, Ullah and Chen.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Auteurs

Sajid Ur Rahman (SU)

School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
College of Animal Science and Technology, Anhui Agricultural University, Hefei, China.

Tzu-Nin Weng (TN)

Department of Stomatology, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi, Taiwan.

Abdul Qadeer (A)

Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
Department of Cell Biology, School of Life Sciences, Central South University, Changsha, China.

Saqib Nawaz (S)

Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.

Hanif Ullah (H)

Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.
West China Hospital, School of Nursing, Sichuan University, Chengdu, China.

Chien-Chin Chen (CC)

Department of Pathology, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi, Taiwan.
Department of Cosmetic Science, Chia Nan University of Pharmacy and Science, Tainan, Taiwan.
Department of Biotechnology and Bioindustry Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, Taiwan.
Doctoral Program in Translational Medicine, Rong Hsing Research Center for Translational Medicine, National Chung Hsing University, Taichung, Taiwan.

Classifications MeSH