Metabolite Study and Structural Authentication for the First-in-Human Use Sphingosine-1-phosphate Receptor 1 Radiotracer.

N-oxide S1PR1 [11C]CS1P1 [18F]FS1P1 [18F]TZ82121 human clinical study radiometabolite radiosynthesis

Journal

ACS chemical neuroscience
ISSN: 1948-7193
Titre abrégé: ACS Chem Neurosci
Pays: United States
ID NLM: 101525337

Informations de publication

Date de publication:
18 Apr 2024
Historique:
medline: 18 4 2024
pubmed: 18 4 2024
entrez: 18 4 2024
Statut: aheadofprint

Résumé

The sphingosine-1-phosphate receptor 1 (S1PR1) radiotracer [

Identifiants

DOI: 10.1021/acschemneuro.4c00077 PMID: 38634759
pubmed: 38634759
doi: 10.1021/acschemneuro.4c00077
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Lin Qiu (L)

Department of Radiology, Washington University School of Medicine, Saint Louis, Missouri 63110, United States.
ORCID: 0000-0001-8823-4132

Hao Jiang (H)

Department of Radiology, Washington University School of Medicine, Saint Louis, Missouri 63110, United States.

Kevin Cho (K)

Center for Mass Spectrometry and Metabolic Tracing, Department of Chemistry, Department of Medicine, Washington University, Saint Louis, Missouri 63130, United States.
ORCID: 0000-0002-3041-3506

Yanbo Yu (Y)

Department of Radiology, Washington University School of Medicine, Saint Louis, Missouri 63110, United States.

Lynne A Jones (LA)

Department of Radiology, Washington University School of Medicine, Saint Louis, Missouri 63110, United States.

Tianyu Huang (T)

Department of Radiology, Washington University School of Medicine, Saint Louis, Missouri 63110, United States.
ORCID: 0000-0002-5607-4901

Joel S Perlmutter (JS)

Department of Radiology, Washington University School of Medicine, Saint Louis, Missouri 63110, United States.
Departments of Neurology, Neuroscience, Physical Therapy and Occupational Therapy, Washington University School of Medicine, Saint Louis, Missouri 63110, United States.

Robert J Gropler (RJ)

Department of Radiology, Washington University School of Medicine, Saint Louis, Missouri 63110, United States.

Matthew R Brier (MR)

Departments of Neurology, Neuroscience, Physical Therapy and Occupational Therapy, Washington University School of Medicine, Saint Louis, Missouri 63110, United States.

Gary J Patti (GJ)

Center for Mass Spectrometry and Metabolic Tracing, Department of Chemistry, Department of Medicine, Washington University, Saint Louis, Missouri 63130, United States.
ORCID: 0000-0002-3748-6193

Tammie L S Benzinger (TLS)

Department of Radiology, Washington University School of Medicine, Saint Louis, Missouri 63110, United States.

Zhude Tu (Z)

Department of Radiology, Washington University School of Medicine, Saint Louis, Missouri 63110, United States.
ORCID: 0000-0003-0325-835X

Classifications MeSH