Two New Phenylpropanoid Compounds from Lilium Brownii and Their Anti-monoamine Oxidase Activity.

Lilium brownii, Baihe, phenylpropanoid, structural elucidation, anti-monoamine oxidase activity

Journal

Chemistry & biodiversity
ISSN: 1612-1880
Titre abrégé: Chem Biodivers
Pays: Switzerland
ID NLM: 101197449

Informations de publication

Date de publication:
18 Apr 2024
Historique:
revised: 17 04 2024
received: 01 03 2024
accepted: 18 04 2024
medline: 18 4 2024
pubmed: 18 4 2024
entrez: 18 4 2024
Statut: aheadofprint

Résumé

Baihe is a commonly used Chinese medicine for the treatment of neurological disorders. Clinically, the bulbs of Lilium brownii are used to act as Baihe. In the study, two new phenylpropanoid compounds including 3-O-acetyl-1-O-caffeoylglycerol (1) and 3-O-acetyl-1-O-p-coumaroylglycerol (2) were isolated from the bulbs of L. brownii. Their structures were identified by spectroscopic method and the effect on monoamine oxidase activity was determined using an enzyme labeling method. The results show 1 and 2 have anti-monoamine oxidase activity with 20.96% and 22.31% inhibition rates at 50 μg/ml, respectively.

Identifiants

pubmed: 38634793
doi: 10.1002/cbdv.202400524
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e202400524

Informations de copyright

© 2024 Wiley‐VCH GmbH.

Auteurs

Chengcheng Hui (C)

Henan University of Chinese Medicine, Department of Pharmacy, JinshuiEast Road, Zhengzhou 450046, China, Zhengzhou, CHINA.

Shuaibo He (S)

Henan University of Chinese Medicine, Department of Pharmacy, JinshuiEast Road, Zhengzhou 450046, China, Zhengzhou, CHINA.

Mengshan Ji (M)

Henan University of Chinese Medicine, Department of Pharmacy, JinshuiEast Road, Zhengzhou 450046, China, Zhengzhou, CHINA.

Yuhang Zhang (Y)

Henan University of Chinese Medicine, The Second Clinical Medical College, JinshuiEast Road, Zhengzhou 450046, China, Zhengzhou, CHINA.

Haibo Wang (H)

Henan Institute for Drug and Medical Device Inspection, NMPA Key Laboratory for Quality Control of Traditional Chinese Medicine, Zhengzhou 450018, China, Zhengzhou, CHINA.

Xiaowei Wang (X)

Henan Institute for Drug and Medical Device Inspection, NMPA Key Laboratory for Quality Control of Traditional Chinese Medicine, Zhengzhou 450018, China, Zhengzhou, CHINA.

Tao Guo (T)

Henan University of Chinese Medicine, Department of Pharmacy, NO 156 Jinshui East Road, Zhengzhou, Henan Province, China, 450046, Zhengzhou, CHINA.

Classifications MeSH