Rescue intrauterine insemination in women failing to retrieve oocytes at ovum pick-up: report of a case series.
IVF
Intrauterine insemination
Oocyte
Pick-up
Journal
Journal of assisted reproduction and genetics
ISSN: 1573-7330
Titre abrégé: J Assist Reprod Genet
Pays: Netherlands
ID NLM: 9206495
Informations de publication
Date de publication:
18 Apr 2024
18 Apr 2024
Historique:
received:
20
10
2023
accepted:
07
03
2024
medline:
18
4
2024
pubmed:
18
4
2024
entrez:
18
4
2024
Statut:
aheadofprint
Résumé
Failure to collect oocytes at the time of oocyte pick-up is an unfavorable outcome of in vitro fertilization (IVF) cycles. In these cases, prompt intrauterine insemination (IUI) could be an option (rescue IUI), but this possibility has been poorly studied. Rescue IUI is routinely offered in our unit in women failing to retrieve oocytes, provided that they have at least one patent tube, normal male semen analysis, and the total number of developed follicles is ≤ 3. We therefore reviewed all oocyte retrievals performed from 2006 to 2022 in our unit to identify these cases. As a comparator, we referred to preplanned IUI performed during the same study period. The 95% confidence interval (95% CI) of proportions was calculated using a binomial distribution model. Rescue IUI was performed in 96 out of 3531 oocyte retrievals (2.7%; 95% CI 2.2-3.3%). Six live births were obtained, corresponding to 6.2% (95% CI 2.3-13.1). All pregnancies were singletons. Rescue IUI in women failing to retrieve oocytes is a possible option that may be considered in selected cases. The efficacy is low, but the procedure is simple, and without significant risks. Generalizability to a conventional IVF protocol setting is however limited.
Identifiants
pubmed: 38635024
doi: 10.1007/s10815-024-03091-z
pii: 10.1007/s10815-024-03091-z
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024. The Author(s).
Références
Abbara A, Clarke SA, Dhillo WS. Novel concepts for inducing final oocyte maturation in in vitro fertilization treatment. Endocr Rev. 2018;39(5):593–628. https://doi.org/10.1210/er.2017-00236 .
doi: 10.1210/er.2017-00236
pubmed: 29982525
pmcid: 6173475
Matorras R, Aparicio V, Corcostegui B, Prieto B, Mendoza R, Ramón O, Gomez-Picado O, Exposito A. Failure of intrauterine insemination as rescue treatment in low responders with adequate HCG timing with no oocytes retrieved. Reprod Biomed Online. 2014;29(5):634–9. https://doi.org/10.1016/j.rbmo.2014.07.020 .
doi: 10.1016/j.rbmo.2014.07.020
pubmed: 25263264
Nargund G, Fauser BC, Macklon NS, Ombelet W, Nygren K, Frydman R, Rotterdam ISMAAR Consensus Group on Terminology for Ovarian Stimulation for IVF. The ISMAAR proposal on terminology for ovarian stimulation for IVF. Hum Reprod. 2007;22(11):2801–4. https://doi.org/10.1093/humrep/dem285 .
doi: 10.1093/humrep/dem285
pubmed: 17855409
World Health Organization. WHO laboratory manual for the examination and processing of human semen. 6th ed. Geneva: Switzerland WHO Press; 2021.
World Health Organization. WHO laboratory manual for the examination and processing of human semen. 5th ed. Geneva: Switzerland WHO Press; 2010.
World Health Organization. WHO laboratory manual for the examination of human semen and semen cervical mucus interaction. 4th ed. Cambridge: World Health Organization. Cambridge University Press; 1999.
Ragni G, Caliari I, Nicolosi AE, Arnoldi M, Somigliana E, Crosignani PG. Preventing high-order multiple pregnancies during controlled ovarian hyperstimulation and intrauterine insemination: 3 years’ experience using low-dose recombinant follicle-stimulating hormone and gonadotropin-releasing hormone antagonists. Fertil Steril. 2006;85(3):619–24. https://doi.org/10.1016/j.fertnstert.2005.09.021 .
doi: 10.1016/j.fertnstert.2005.09.021
pubmed: 16500328
Ferraretti AP, La Marca A, Fauser BC, Tarlatzis B, Nargund G, Gianaroli L, ESHRE working group on Poor Ovarian Response Definition. ESHRE consensus on the definition of “poor response” to ovarian stimulation for in vitro fertilization: the Bologna criteria. Hum Reprod. 2011;26(7):1616–24.
doi: 10.1093/humrep/der092
pubmed: 21505041
Immediata V, Patrizio P, Parisen Toldin MR, Morenghi E, Ronchetti C, Cirillo F, Baggiani A, Albani E, Levi-Setti PE. Twenty-one year experience with intrauterine inseminations after controlled ovarian stimulation with gonadotropins: maternal age is the only prognostic factor for success. J Assist Reprod Genet. 2020;37(5):1195–201.
doi: 10.1007/s10815-020-01752-3
pubmed: 32215826
pmcid: 7244676
Zippl AL, Wachter A, Rockenschaub P, Toth B, Seeber B. Predicting success of intrauterine insemination using a clinically based scoring system. Arch Gynecol Obstet. 2022;306(5):1777–86.
pubmed: 36069921
pmcid: 9519724
Revelli A, Carosso A, Grassi G, Gennarelli G, Canosa S, Benedetto C. Empty follicle syndrome revisited: definition, incidence, aetiology, early diagnosis and treatment. Reprod Biomed Online. 2017;35(2):132–8. https://doi.org/10.1016/j.rbmo.2017.04.012 .
doi: 10.1016/j.rbmo.2017.04.012
pubmed: 28596003
Nargund G, Reid F, Parsons J. Human chorionic gonadotropin-to-oocyte collection interval in a superovulation IVF program. A prospective study. J Assist Reprod Genet. 2001;18(2):87–90. https://doi.org/10.1023/a:1026530624575 .
doi: 10.1023/a:1026530624575
pubmed: 11285986
pmcid: 3455552
Stevenson TL, Lashen H. Empty follicle syndrome: the reality of a controversial syndrome, a systematic review. Fertil Steril. 2008;90(3):691–8. https://doi.org/10.1016/j.fertnstert.2007.07.1312 .
doi: 10.1016/j.fertnstert.2007.07.1312
pubmed: 18023430
Sunkara SK, Rittenberg V, Raine-Fenning N, Bhattacharya S, Zamora J, Coomarasamy A. Association between the number of eggs and live birth in IVF treatment: an analysis of 400 135 treatment cycles. Hum Reprod. 2011;26(7):1768–74.
doi: 10.1093/humrep/der106
pubmed: 21558332
Somigliana E, Paffoni A, Busnelli A, Cardellicchio L, Leonardi M, Filippi F, Ragni G, Fedele L. IVF outcome in poor responders failing to produce viable embryos in the preceding cycle. Reprod Biomed Online. 2013;26(6):569–76. https://doi.org/10.1016/j.rbmo.2013.02.013 .
doi: 10.1016/j.rbmo.2013.02.013
pubmed: 23602683