Behavioral and dysexecutive variant of Alzheimer's disease: Insights from structural and molecular imaging studies.
Behavioral and dysexecutive AD phenotypes
Frontal variant Alzheimer's disease
Molecular imaging
Structural imaging
Journal
Heliyon
ISSN: 2405-8440
Titre abrégé: Heliyon
Pays: England
ID NLM: 101672560
Informations de publication
Date de publication:
30 Apr 2024
30 Apr 2024
Historique:
received:
28
09
2023
revised:
02
04
2024
accepted:
08
04
2024
medline:
19
4
2024
pubmed:
19
4
2024
entrez:
19
4
2024
Statut:
epublish
Résumé
Frontal variant Alzheimer's disease (AD) manifests with either behavioral or dysexecutive syndromes. Recent efforts to gain a deeper understanding of this phenotype have led to a re-conceptualization of frontal AD. Behavioral (bAD) and dysexecutive (dAD) phenotypes could be considered subtypes, as suggested by both clinical and neuroimaging studies. In this review, we focused on imaging studies to highlight specific brain patterns in these two uncommon clinical AD phenotypes. Although studies did not compare directly these two variants, a common epicenter located in the frontal cortex could be inferred. On the contrary, 18
Identifiants
pubmed: 38638964
doi: 10.1016/j.heliyon.2024.e29420
pii: S2405-8440(24)05451-3
pmc: PMC11024599
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
e29420Informations de copyright
© 2024 The Author(s).
Déclaration de conflit d'intérêts
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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