Liver-targeted polymeric prodrugs delivered subcutaneously improve tafenoquine therapeutic window for malaria radical cure.

Journal

Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440

Informations de publication

Date de publication:
19 Apr 2024
Historique:
medline: 19 4 2024
pubmed: 19 4 2024
entrez: 19 4 2024
Statut: ppublish

Résumé

Approximately 3.3 billion people live with the threat of

Identifiants

DOI: 10.1126/sciadv.adk4492 PMID: 38640243
pubmed: 38640243
doi: 10.1126/sciadv.adk4492
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eadk4492

Auteurs

Ayumi E Pottenger (AE)

Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.
ORCID: 0000-0002-0383-2975

Debashish Roy (D)

Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.
ORCID: 0009-0009-9940-1907

Selvi Srinivasan (S)

Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.

Thomas E J Chavas (TEJ)

Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.

Vladmir Vlaskin (V)

Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.

Duy-Khiet Ho (DK)

Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.

Vincent C Livingston (VC)

Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.

Mahdi Maktabi (M)

Department of Immunology and Microbiology, University of Colorado Anschutz School of Medicine, Aurora, CO 80045, USA.
ORCID: 0000-0003-3083-2564

Hsiuling Lin (H)

Department of Drug Discovery, Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
ORCID: 0009-0006-6961-2330

Jing Zhang (J)

Department of Drug Discovery, Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.

Brandon Pybus (B)

Department of Drug Discovery, Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
ORCID: 0000-0002-0392-225X

Karl Kudyba (K)

Department of Drug Discovery, Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
ORCID: 0000-0001-5681-321X

Alison Roth (A)

Department of Drug Discovery, Experimental Therapeutics Branch, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
ORCID: 0000-0001-6917-3485

Peter Senter (P)

Seagen, Bothell, WA 98021, USA.

George Tyson (G)

George Tyson Consulting, Los Altos Hills, CA 94022, USA.
Department of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, CA 94720, USA.
ORCID: 0009-0002-4840-5085

Hans E Huber (HE)

BioTD Strategies LLC, 213 Abbey Ln., Lansdale, PA 19446, USA.
ORCID: 0000-0002-2224-8192

David Wesche (D)

Certara, Princeton, NJ 08540, USA.
ORCID: 0000-0002-3383-9238

Rosemary Rochford (R)

Department of Immunology and Microbiology, University of Colorado Anschutz School of Medicine, Aurora, CO 80045, USA.

Paul A Burke (PA)

Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.
Burke Bioventures LLC, 1 Broadway 14th Floor, Cambridge, MA 02142, USA.
ORCID: 0000-0002-5721-0792

Patrick S Stayton (PS)

Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.
ORCID: 0000-0001-6939-6371

Classifications MeSH