The effect of electron backscatter and charge build up in media on beam current transformer signal for ultra-high dose rate (FLASH) electron beam monitoring.

Beam current transformer Charge build-up Electron UHDR radiotherapy FLASH radiotherapy Ultra-high dose rate radiotherapy

Journal

Physics in medicine and biology
ISSN: 1361-6560
Titre abrégé: Phys Med Biol
Pays: England
ID NLM: 0401220

Informations de publication

Date de publication:
19 Apr 2024
Historique:
medline: 20 4 2024
pubmed: 20 4 2024
entrez: 19 4 2024
Statut: aheadofprint

Résumé

Beam current transformers (BCT) are promising detectors for real-time beam monitoring in ultra-high dose rate (UHDR) electron radiotherapy. However, previous studies have reported a significant sensitivity of the BCT signal to changes in source-to-surface distance (SSD), field size, and phantom material which have until now been attributed to the fluctuating levels of electrons backscattered within the BCT. The purpose of this study is to evaluate this hypothesis, with the goal of understanding and mitigating the variations in BCT signal due to changes in irradiation 

Approach: Monte Carlo simulations and experimental measurements were conducted with a UHDR-capable intra-operative electron linear accelerator to analyze the impact of backscattered electrons on BCT signal. The potential influence of charge accumulation in media as a mechanism affecting BCT signal perturbation was further investigated by examining the effects phantom conductivity and electrical grounding. Finally, the effectiveness of Faraday shielding to mitigate BCT signal variations is evaluated. 

Main Results: Monte Carlo simulations indicated that the fraction of electrons backscattered in water and on the collimator plastic at 6 and 9 MeV is lower than 1%, suggesting that backscattered electrons alone cannot account for the observed BCT signal variations. However, our experimental measurements confirmed previous findings of BCT response variation up to 15% for different field diameters. A significant impact of phantom type on BCT response was also observed, with variations in BCT signal as high as 14.1% when comparing measurements in water and solid water. The introduction of a Faraday shield to our applicators effectively mitigated the dependencies of BCT signal on SSD, field size, and phantom material.

Significance: Our results indicate that variations in BCT signal as a function of SSD, field size, and phantom material are likely driven by an electric field originating in dielectric materials exposed to the UHDR electron beam. Strategies such as Faraday shielding were shown to effectively prevent these electric fields from affecting BCT signal, enabling reliable BCT-based electron UHDR beam monitoring.

Identifiants

pubmed: 38640916
doi: 10.1088/1361-6560/ad40f7
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Creative Commons Attribution license.

Auteurs

Charles Pageot (C)

Département de Génie Physique, Polytechnique Montreal, 2500 Chem. de Polytechnique, Montréa, Montreal, Quebec, H3T 1J4, CANADA.

Karim Zerouali (K)

Radio-Oncologie, Centre Hospitalier de l'Université de Montréal, 1000 St-Denis Street, Montreal, Quebec, H2W 1T8, CANADA.

Dominique Guillet (D)

Radio-Oncologie, Centre Hospitalier de l'Université de Montréal, 1000 St-Denis Street, Montreal, Quebec, H2W 1T8, CANADA.

Bryan Richard Muir (BR)

Metrology Research Centre, NRC, 1200 Montreal Road, Ottawa, Ontario, K1A 0R6, CANADA.

James Renaud (J)

Metrology Research Centre, NRC, 1200 Montreal Road, Ottawa, Ontario, K1A 0R6, CANADA.

Arthur Lalonde (A)

Physics, Universite de Montreal, 1375 Ave.Thérèse-Lavoie-Roux, Montreal, Quebec, H3C 3J7, CANADA.

Classifications MeSH