Levamisole in childhood idiopathic nephrotic syndrome: new promises, and advocacy for global access.


Journal

Kidney international
ISSN: 1523-1755
Titre abrégé: Kidney Int
Pays: United States
ID NLM: 0323470

Informations de publication

Date de publication:
May 2024
Historique:
received: 13 11 2023
revised: 29 11 2023
accepted: 02 01 2024
medline: 21 4 2024
pubmed: 21 4 2024
entrez: 20 4 2024
Statut: ppublish

Résumé

In the current issue of Kidney International, Sinha et al. present data from an open-label, noninferior, randomized controlled trial comparing 12-months of alternate-day prednisolone, given daily during infection, versus levamisole, in children with frequently relapsing or steroid-dependent nephrotic syndrome. This study suggests that both of these strategies are efficacious and safe. Results of this study should redefine the role of levamisole in future guidelines, and a call for global availability of levamisole should be advocated.

Identifiants

pubmed: 38642993
pii: S0085-2538(24)00095-4
doi: 10.1016/j.kint.2024.01.030
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

932-934

Informations de copyright

Copyright © 2024 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.

Auteurs

Eugene Yu-Hin Chan (EY)

Paediatric Nephrology Centre, Hong Kong Children's Hospital, Department of Paediatrics, Chinese University of Hong Kong, Shatin, Hong Kong SAR. Electronic address: genegene.chan@gmail.com.

Olivia Boyer (O)

Pediatric Nephrology, Reference Center for Idiopathic Nephrotic Syndrome in Children and Adults, Necker - Enfants Malades University Hospital, APHP, Inserm U1163, Imagine Institute, Paris Cité University, Paris, France. Electronic address: Olivia.boyer@aphp.fr.

Classifications MeSH