Aberrant sparganosis in cat caused by Spirometra mansoni (Cestoda: Diphyllobothriidae): a case report.

Felis silvestris catus Spirometra mansoni Domestic cat Next-generation sequencing Paraffin-embedded tissue Sequence analysis

Journal

BMC veterinary research
ISSN: 1746-6148
Titre abrégé: BMC Vet Res
Pays: England
ID NLM: 101249759

Informations de publication

Date de publication:
20 Apr 2024
Historique:
received: 22 11 2023
accepted: 27 03 2024
medline: 21 4 2024
pubmed: 21 4 2024
entrez: 20 4 2024
Statut: epublish

Résumé

Sparganosis is a rare zoonotic disease caused by plerocercoid larvae of the genera Spirometra or Sparganum (Cestoda: Diphyllobothriidae). The larvae of Spirometra generally do not undergo asexual reproduction, whereas those of Sparganum can induce proliferative lesions in infected tissues. This paper presents an unusual case of proliferative sparganosis due to infection with Spirometra mansoni in a cat, normally considered a definitive host of the species. A 9-year-old male domestic cat was presented with a mass on the right side of the face that underwent progressive enlargement for 1 month. The morphological and histopathological examinations revealed multiple asexual proliferative cestode larvae in the lesions, suggestive of proliferative sparganosis. Next-generation sequencing analysis of formalin-fixed and paraffin-embedded specimens of surgically excised tissue indicated that the worm was Spirometra mansoni. Although S. mansoni a common tapeworm species found in the small intestine of domestic cats and dogs in Japan, proliferative sparganosis is extremely rare. This is the first confirmed case of proliferative sparganosis due to infection with S. mansoni in cat.

Sections du résumé

BACKGROUND BACKGROUND
Sparganosis is a rare zoonotic disease caused by plerocercoid larvae of the genera Spirometra or Sparganum (Cestoda: Diphyllobothriidae). The larvae of Spirometra generally do not undergo asexual reproduction, whereas those of Sparganum can induce proliferative lesions in infected tissues. This paper presents an unusual case of proliferative sparganosis due to infection with Spirometra mansoni in a cat, normally considered a definitive host of the species.
CASE PRESENTATION METHODS
A 9-year-old male domestic cat was presented with a mass on the right side of the face that underwent progressive enlargement for 1 month. The morphological and histopathological examinations revealed multiple asexual proliferative cestode larvae in the lesions, suggestive of proliferative sparganosis. Next-generation sequencing analysis of formalin-fixed and paraffin-embedded specimens of surgically excised tissue indicated that the worm was Spirometra mansoni.
CONCLUSION CONCLUSIONS
Although S. mansoni a common tapeworm species found in the small intestine of domestic cats and dogs in Japan, proliferative sparganosis is extremely rare. This is the first confirmed case of proliferative sparganosis due to infection with S. mansoni in cat.

Identifiants

pubmed: 38643141
doi: 10.1186/s12917-024-03995-z
pii: 10.1186/s12917-024-03995-z
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

148

Subventions

Organisme : Japan Society for the Promotion of Science
ID : 19H03212
Organisme : JST CREST
ID : JPMJCR18S7

Informations de copyright

© 2024. The Author(s).

Références

Kikuchi T, Maruyama H. Human proliferative sparganosis update. Parasitol Int. 2020;75:102036. https://doi.org/10.1016/j.parint.2019.102036 .
doi: 10.1016/j.parint.2019.102036 pubmed: 31841658
Kikuchi T, Dayi M, Hunt VL, Ishiwata K, Toyoda A, Kounosu A, Sun S, Maeda Y, Kondo Y, de Noya BA, Noya O, Kojima S, Kuramochi T, Maruyama H. Genome of the fatal tapeworm Sparganum proliferum uncovers mechanisms for cryptic life cycle and aberrant larval proliferation. Commun Biol. 2021;4:649. https://doi.org/10.1038/s42003-021-02160-8 .
doi: 10.1038/s42003-021-02160-8 pubmed: 34059788 pmcid: 8166898
Marcelino VR, Clausen PTLC, Buchmann JP, Wille M, Iredell JR, Meyer W, Lund O, Sorrell TC, Holmes EC. CCMetagen: comprehensive and accurate identification of eukaryotes and prokaryotes in metagenomic data. Genome Biol. 2020;21:103. https://doi.org/10.1186/s13059-020-02014-2 .
doi: 10.1186/s13059-020-02014-2 pubmed: 32345331 pmcid: 7189439
Jin JJ, Yu WB, Yang JB, Song Y, dePamphilis CW, Yi TS, Li DZ. GetOrganelle: a fast and versatile toolkit for accurate de novo assembly of organelle genomes. Genome Biol. 2020;21:241. https://doi.org/10.1186/s13059-020-02154-5 .
doi: 10.1186/s13059-020-02154-5 pubmed: 32912315 pmcid: 7488116
Yamasaki H, Sanpool O, Rodpai R, Sadaow L, Laummaunwai P, Un M, Thanchomnang T, Laymanivong S, Aung WPP, Intapan PM, Maleewong W. Spirometra species from Asia: genetic diversity and taxonomic challenges. Parasitol Int. 2021;80:102181. https://doi.org/10.1016/j.parint.2020.102181 .
doi: 10.1016/j.parint.2020.102181 pubmed: 32898662
Kuchta R, Kołodziej-Sobocińska M, Brabec J, Młocicki D, Sałamatin R, Scholz T. Sparganosis (Spirometra) in Europe in the molecular era. Clin Infect Dis. 2021;72:882–90. https://doi.org/10.1093/cid/ciaa1036 .
doi: 10.1093/cid/ciaa1036 pubmed: 32702118
Yamasaki H, Sugiyama H, Morishima Y, Kobayashi H. Description of Spirometra asiana sp. nov. (Cestoda: Diphyllobothriidae) found in wild boars and hound dogs in Japan. Parasitol Int. 2023;98. https://doi.org/10.1016/j.parint.2023.102798 .
Muller JF. The biology of Spirometra. J Parasitol. 1974;60:3–14.
Schmidt RE, Reid JS, Garnere FM. Sparganosis in a cat. J Small Anim Pract. 1968;9:551–3.
doi: 10.1111/j.1748-5827.1968.tb04581.x pubmed: 5749576
Uga S, Goto M, Matsumura T, Kagei N. Natural infection of Sparganum mansoni in cats captured in Hyogo Prefecture, Japan. Jpn J Parastiol. 1986;35:153–9.
Buergelt CD, Greiner EC, Senior DF. Proliferative sparganosis in a cat. J Parasitol. 1984;70:121–5. https://doi.org/10.2307/3281933 .
doi: 10.2307/3281933 pubmed: 6737156
Woldemeskel M. Subcutaneous sparganosis, a zoonotic cestodiasis, in two cats. J Vet Diagn Invest. 2014;26:316–9. https://doi.org/10.1177/1040638713517697 .
doi: 10.1177/1040638713517697 pubmed: 24464556

Auteurs

Toshihiro Tokiwa (T)

Laboratory of Veterinary Parasitology, Nippon Veterinary and Life Science University, Kyonancho, Musashino, Tokyo, Japan. tokiwa@nvlu.ac.jp.

Momo Fushimi (M)

Fushimi Animal Hospital, Hanawa, Mashikomachi, Hagagun, Tochigi, Japan.

Shyun Chou (S)

Laboratory of Veterinary Parasitology, Nippon Veterinary and Life Science University, Kyonancho, Musashino, Tokyo, Japan.
Department of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, Xing Da Road, Taichung, Taiwan.

Akemi Yoshida (A)

Genomics and Bioenvironmental Science, Frontier Science Research Center, University of Miyazaki, Miyazaki, Japan.

Kensei Kinoshita (K)

Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan.

Atsushi Hikima (A)

Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan.

Taisei Kikuchi (T)

Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan.
Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.

Kiyokazu Ozaki (K)

Laboratory of Pathology, Setsunan University, Nagaotohgecho, Hirakata, Osaka, Japan.

Classifications MeSH