The great imitator: Tuberculosis with lymphadenopathy and splenomegaly.

Atypical presentations Extrapulmonary tuberculosis Hodgkin lymphoma Mycobacterium tuberculosis complex Reed-Sternberg cells Tuberculous lymphadenitis

Journal

IDCases
ISSN: 2214-2509
Titre abrégé: IDCases
Pays: Netherlands
ID NLM: 101634540

Informations de publication

Date de publication:
2024
Historique:
received: 21 12 2023
revised: 18 02 2024
accepted: 14 04 2024
medline: 22 4 2024
pubmed: 22 4 2024
entrez: 22 4 2024
Statut: epublish

Résumé

Tuberculosis (TB) is a leading infectious killer worldwide. Over two-thirds of new TB diagnoses in the United States occur among first-generation immigrants, especially within a year of migration. Hodgkin lymphoma (HL) accounts for a minority of lymphoma cases but presents similarly to disseminated or extrapulmonary TB. Clinical overlap between TB and HL increases patient risk of misdiagnosis. Concomitant presentation of both diseases is not uncommon but infrequently reported. We present a case of isoniazid-resistant TB with progressively worsening lymphadenopathy and splenomegaly despite appropriate TB treatment. The patient was diagnosed with HL following PET/CT and axillary lymph node biopsy.

Identifiants

pubmed: 38646597
doi: 10.1016/j.idcr.2024.e01968
pii: S2214-2509(24)00044-1
pmc: PMC11031776
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e01968

Informations de copyright

© 2024 The Authors. Published by Elsevier Ltd.

Déclaration de conflit d'intérêts

None.

Auteurs

Ashton D Hall (AD)

Division of Infectious Diseases, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Laura Victoria Medina Rodriguez (LVM)

Universidad Peruana de Ciencias Aplicadas, Lima, Peru.

Jared Vearrier (J)

Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Kavya Patel (K)

Division of Infectious Diseases, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Bryan C Hambley (BC)

Division of Hematology and Oncology, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Moises A Huaman (MA)

Division of Infectious Diseases, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Classifications MeSH