Mouse Anesthesia and Analgesia.

analgesia anesthesia mouse multimodal analgesia pain post‐operative care rodent

Journal

Current protocols

ISSN: 2691-1299

Titre abrégé: Curr Protoc

Pays: United States

ID NLM: 101773894

Informations de publication

Date de publication:
Apr 2024

Historique:

medline: 22 4 2024

pubmed: 22 4 2024

entrez: 22 4 2024

Statut: ppublish

Résumé

Providing anesthesia and analgesia for mouse subjects is a common and critical practice in the laboratory setting. This practice is necessary for performing invasive procedures, achieving prolonged immobility for sensitive imaging modalities (magnetic resonance imaging, for instance), and providing intra- and post-procedural pain relief. In addition to facilitating the procedures performed by the investigator, the provision of anesthesia and analgesia is crucial for the preservation of animal welfare and for humane treatment of animals used in research. Furthermore, anesthesia and analgesia are important components of animal use protocols reviewed by Institutional Animal Care and Use Committees, requiring careful consideration and planning for the particular animal model. In this article, we provide technical guidance for the investigator, covering the provision of anesthesia by two routes (injectable and inhalant), guidelines for monitoring anesthesia, current techniques for recognition of pain, considerations for administering preventative analgesia, and considerations for post-operative care. © 2024 Wiley Periodicals LLC. Basic Protocol 1: Injectable anesthesia Basic Protocol 2: Inhalant anesthesia Basic Protocol 3: Assessing pain.

Identifiants

DOI: 10.1002/cpz1.1006 PMID: 38646951

pubmed: 38646951

doi: 10.1002/cpz1.1006

doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

Pagination

e1006

Informations de copyright

Références

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