Lead exerts a depression of neurotransmitter release through a blockade of voltage dependent calcium channels in chromaffin cells.

Chromaffin cells calcium channels catecholamines cellular excitability lead neurotransmitter release

Journal

Toxicology
ISSN: 1879-3185
Titre abrégé: Toxicology
Pays: Ireland
ID NLM: 0361055

Informations de publication

Date de publication:
20 Apr 2024
Historique:
received: 22 01 2024
revised: 08 04 2024
accepted: 17 04 2024
medline: 23 4 2024
pubmed: 23 4 2024
entrez: 22 4 2024
Statut: aheadofprint

Résumé

The present work, using chromaffin cells of bovine adrenal medullae (BCCs), aims to describe what type of ionic current alterations induced by lead (Pb

Identifiants

pubmed: 38648961
pii: S0300-483X(24)00090-8
doi: 10.1016/j.tox.2024.153809
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

153809

Informations de copyright

Copyright © 2024. Published by Elsevier B.V.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests. Jesus Miguel Hernandez Guijo reports financial support was provided by Ministerio de Ciencia, Innovación y Universidades. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper

Auteurs

Victoria Jiménez Carretero (VJ)

Department of Pharmacology and Therapeutic, Facultad de Medicina, Univ. Autónoma de Madrid, Av. Arzobispo Morcillo 4, 28029 Madrid, Spain.

Ninfa Liccardi (N)

Department of Pharmacology and Therapeutic, Facultad de Medicina, Univ. Autónoma de Madrid, Av. Arzobispo Morcillo 4, 28029 Madrid, Spain.

Maria Arribas Tejedor (MA)

Department of Pharmacology and Therapeutic, Facultad de Medicina, Univ. Autónoma de Madrid, Av. Arzobispo Morcillo 4, 28029 Madrid, Spain.

Ricardo de Pascual (R)

Department of Pharmacology and Therapeutic, Facultad de Medicina, Univ. Autónoma de Madrid, Av. Arzobispo Morcillo 4, 28029 Madrid, Spain.

Jorge Hernández Campano (JH)

Department of Pharmacology and Therapeutic, Facultad de Medicina, Univ. Autónoma de Madrid, Av. Arzobispo Morcillo 4, 28029 Madrid, Spain.

Jesús M Hernández-Guijo (JM)

Department of Pharmacology and Therapeutic, Facultad de Medicina, Univ. Autónoma de Madrid, Av. Arzobispo Morcillo 4, 28029 Madrid, Spain; Ramón y Cajal Institute for Health Research, IRYCIS, Hospital Ramón y Cajal, Ctra. de Colmenar Viejo, Km. 9,100, 28029 Madrid, Spain. Electronic address: jesusmiguel.hernandez@uam.es.

Classifications MeSH