Medical Conditions in Former Professional American-Style Football Players Are Associated With Self-Reported Clinical Features of Traumatic Encephalopathy Syndrome.

chronic traumatic encephalopathy comorbidities concussion encephalopathy syndrome football traumatic encephalopathy syndrome

Journal

Neurotrauma reports
ISSN: 2689-288X
Titre abrégé: Neurotrauma Rep
Pays: United States
ID NLM: 101773091

Informations de publication

Date de publication:
2024
Historique:
medline: 24 4 2024
pubmed: 24 4 2024
entrez: 24 4 2024
Statut: epublish

Résumé

Consensus criteria for traumatic encephalopathy syndrome (TES) specify that at least one core clinical feature of cognitive impairment (CI; e.g., difficulties with memory, executive function) or neurobehavioral dysregulation (ND; e.g., explosiveness, rage, and mood lability) be present and not fully accounted for by other health disorders. Associations between self-reported symptoms that mirror the core clinical features of TES-and how they may be related to concomitant medical conditions-remain unclear. The purpose of this study was to evaluate the association of medical conditions and football exposures with TES clinical features (CI

Identifiants

pubmed: 38655114
doi: 10.1089/neur.2024.0008
pii: 10.1089/neur.2024.0008
pmc: PMC11035840
doi:

Types de publication

Journal Article

Langues

eng

Pagination

376-386

Informations de copyright

© Rachel Grashow and Shawn R. Eagle et al., 2024; Published by Mary Ann Liebert, Inc.

Déclaration de conflit d'intérêts

Dr. Zafonte reported receiving royalties from Springer/Demos publishing for serving as coeditor of the text Brain Injury Medicine; serving on the scientific advisory board of Myomo Inc, and onecare.ai Inc; evaluating patients in the Massachusetts General Hospital Brain and Body–TRUST Program, which is funded by the National Football League Players Association (NFLPA); and receiving grants from the NIH. Dr. Baggish has received funding from the NIH/National Heart, Lung, and Blood Institute, the NFLPA, and the American Heart Association and receives compensation for his role as team cardiologist from the U.S. Olympic Committee/U.S. Olympic Training Centers, U.S. Soccer, U.S. Rowing, the New England Patriots, the Boston Bruins, the New England Revolution, and Harvard University. Dr. Taylor reported receiving grants from the NFLPA outside the submitted work and grants from the NIH. Dr. Weisskopf reported receiving grants from the NFLPA and the NIH during the conduct of the study. Dr. Terry serves on the scientific advisory board for HitIQ and previously consulted for REACT Neuro, Inc. Dr. Grashow and Ms. Heather DiGregorio received grant funding from the NFLPA.

Références

Brain Commun. 2021 Jan 25;3(1):fcab001
pubmed: 33842882
J Neurotrauma. 2021 Jan 15;38(2):189-195
pubmed: 32640866
Front Neurol. 2021 Feb 23;12:617526
pubmed: 33708171
Neurology. 2010 Sep 14;75(11):997-1002
pubmed: 20837967
J Adv Pharm Technol Res. 2010 Jul;1(3):297-301
pubmed: 22247861
Am J Public Health. 2014 May;104(5):822-33
pubmed: 24625171
Alzheimers Res Ther. 2014 Sep 24;6(5):68
pubmed: 25580160
J Clin Endocrinol Metab. 2015 Jun;100(6):2223-30
pubmed: 25867811
JAMA Neurol. 2019 Dec 1;76(12):1428-1438
pubmed: 31449296
Endocr Rev. 2014 Jun;35(3):341-75
pubmed: 24423981
Ann Neurol. 2020 Jul;88(1):106-112
pubmed: 32281676
Neurology. 2022 Aug 9;99(6):e594-e604
pubmed: 35577574
Am J Sports Med. 2019 Oct;47(12):2871-2880
pubmed: 31468987
Br J Sports Med. 2023 Apr;57(7):389-394
pubmed: 36517216
Circulation. 2023 Apr 4;147(14):1112-1114
pubmed: 36748510
Am J Ind Med. 2019 Aug;62(8):643-654
pubmed: 31210374
J Neurotrauma. 2022 Sep;39(17-18):1195-1213
pubmed: 35481808
Curr Hypertens Rep. 2013 Dec;15(6):547-58
pubmed: 24146223
JAMA Netw Open. 2022 Jul 1;5(7):e2219934
pubmed: 35796154
Alzheimers Dement. 2021 Oct;17(10):1709-1724
pubmed: 33826224
Neurology. 2012 Jun 5;78(23):1860-7
pubmed: 22573626
Front Neurol. 2021 Apr 14;12:632618
pubmed: 33935940
Neurology. 2021 May 4;96(18):848-863
pubmed: 33722990

Auteurs

Rachel Grashow (R)

Harvard Medical School, Boston, Massachusetts, USA.
Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

Shawn R Eagle (SR)

Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Douglas P Terry (DP)

Vanderbilt Sports Concussion Center, Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Heather DiGregorio (H)

Harvard Medical School, Boston, Massachusetts, USA.

Aaron L Baggish (AL)

Harvard Medical School, Boston, Massachusetts, USA.
Cardiovascular Performance Program, Massachusetts General Hospital, Boston, Massachusetts, USA.
Department of Cardiology, Lausanne University Hospital (CHUV) and Institute for Sport Science, University of Lausanne (ISSUL), Lausanne, Switzerland.

Marc G Weisskopf (MG)

Harvard Medical School, Boston, Massachusetts, USA.
Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

Anthony Kontos (A)

Department of Orthopedic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

David O Okonkwo (DO)

Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Ross Zafonte (R)

Harvard Medical School, Boston, Massachusetts, USA.
Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Charlestown, Massachusetts, USA.
Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, Massachusetts, USA.

Classifications MeSH