Shoulder Lesions Do Not Increase Inflammatory Biomarkers in Patients Undergoing Surgery for Glenohumeral Instability: An Exploratory Study.


Journal

Translational sports medicine
ISSN: 2573-8488
Titre abrégé: Transl Sports Med
Pays: England
ID NLM: 101734315

Informations de publication

Date de publication:
2022
Historique:
received: 18 10 2021
accepted: 10 02 2022
medline: 27 2 2022
pubmed: 27 2 2022
entrez: 24 4 2024
Statut: epublish

Résumé

Circulating protein biomarkers have demonstrated utility as a diagnostic tool in predicting musculoskeletal disease severity, but their utility in the evaluation of shoulder lesions associated with shoulder instability is unknown. Thus, the purpose of this exploratory study was to determine whether preoperative biomarkers of cartilage turnover and inflammation are associated with specific shoulder lesions in shoulder instability. Thirty-three patients (29.9 ± 9.4 years of age, 4.5 ± 4.7 dislocations) undergoing surgical treatment for shoulder instability were assessed for the presence or absence of associated shoulder lesions. Biomarkers including cartilage oligomeric matrix protein (COMP), C-reactive protein (HS-CRP), interleukin-8 (IL-8), and macrophage inflammatory protein-1

Identifiants

pubmed: 38655158
doi: 10.1155/2022/4220356
pmc: PMC11022782
doi:

Types de publication

Journal Article

Langues

eng

Pagination

4220356

Informations de copyright

Copyright © 2022 Jonathan S. Yu et al.

Déclaration de conflit d'intérêts

Dr. Mendias reports research support from GlaxoSmithKline, consultant fees from GLG Consulting, editorial board for Journal of Applied Physiology, Journal of Orthopaedic Research, and Translational Sports Medicine, board member for National Athletic Trainers' Association, and employee for Myognosis. Dr. Rodeo reports consulting fees from Novartis Pharmaceuticals and faculty/speaker fees from Smith & Nephew. Dr. Dines reports consulting fees from Arthrex, Linvatec, Merck Sharpe & Dohme, Trice Medical, Wright Medical Technology, Conmed, and investment in ViewFi Health. No other author has any commercial associations (eg., consultancies, stock ownership, equity interest, patent/licensing arrangements, etc.) that might pose a conflict of interest in connection with the submitted article.

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Auteurs

Jonathan S Yu (JS)

Hospital for Special Surgery, New York, NY, USA.
Weill Cornell Medicine, New York, NY, USA.

David M Dare (DM)

Hospital for Special Surgery, New York, NY, USA.
Raleigh Orthopedic Clinic, Raleigh, NC, USA.

Daniel Edon (D)

Hospital for Special Surgery, New York, NY, USA.

Alec L Sinatro (AL)

Hospital for Special Surgery, New York, NY, USA.
Albert Einstein College of Medicine, New York, NY, USA.

Dylan C Sarver (DC)

Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Department of Orthopaedic Surgery, University of Michigan, Ann Arbor, MI, USA.

Scott Rodeo (S)

Hospital for Special Surgery, New York, NY, USA.
Weill Cornell Medicine, New York, NY, USA.

Joshua S Dines (JS)

Hospital for Special Surgery, New York, NY, USA.
Weill Cornell Medicine, New York, NY, USA.

Christopher L Mendias (CL)

Hospital for Special Surgery, New York, NY, USA.
Weill Cornell Medicine, New York, NY, USA.
Department of Orthopaedic Surgery, University of Michigan, Ann Arbor, MI, USA.

Classifications MeSH