Design, synthesis, biological and computational screening of novel pyridine-based thiadiazole derivatives as prospective anti-inflammatory agents.

Acute toxicity Anti-inflammatory activity Cyclooxygenase-2 In silico studies Pyridine derivatives Thiadiazole derivatives

Journal

Heliyon
ISSN: 2405-8440
Titre abrégé: Heliyon
Pays: England
ID NLM: 101672560

Informations de publication

Date de publication:
30 Apr 2024
Historique:
received: 04 01 2024
revised: 12 03 2024
accepted: 08 04 2024
medline: 24 4 2024
pubmed: 24 4 2024
entrez: 24 4 2024
Statut: epublish

Résumé

In this study, a novel series of pyridine-based thiadiazole derivatives (

Identifiants

pubmed: 38655368
doi: 10.1016/j.heliyon.2024.e29390
pii: S2405-8440(24)05421-5
pmc: PMC11036016
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e29390

Informations de copyright

© 2024 The Authors.

Déclaration de conflit d'intérêts

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Références

Pharmacol Rep. 2020 Oct;72(5):1079-1100
pubmed: 32880874
ACS Omega. 2020 Sep 25;5(39):25228-25239
pubmed: 33043201
Acta Chim Slov. 2019 Feb;66(1):103-111
pubmed: 33855463
ACS Omega. 2023 Mar 16;8(12):11326-11334
pubmed: 37008112
ChemMedChem. 2013 Jan;8(1):27-41
pubmed: 23208773
Inflammopharmacology. 2004;12(1):89-94
pubmed: 15035782
Curr Top Med Chem. 2021 Nov 11;21(28):2546-2573
pubmed: 34766891
Bioorg Med Chem. 2013 Aug 1;21(15):4581-90
pubmed: 23769654
Drug Discov Today. 2020 Jan;25(1):248-258
pubmed: 31705979
Mini Rev Med Chem. 2019;19(6):527-538
pubmed: 30360710
Molecules. 2022 Sep 27;27(19):
pubmed: 36234908
Molecules. 2018 Sep 21;23(10):
pubmed: 30248903
J Agric Food Chem. 2010 Mar 10;58(5):2755-62
pubmed: 20000685
Inflammopharmacology. 2022 Apr;30(2):355-368
pubmed: 35217901
Int J Mol Sci. 2021 Jan 30;22(3):
pubmed: 33573356
Molecules. 2022 Mar 11;27(6):
pubmed: 35335208
Molecules. 2015 Aug 21;20(8):15287-303
pubmed: 26307959
Nucleic Acids Res. 2000 Jan 1;28(1):235-42
pubmed: 10592235
Am Health Drug Benefits. 2019 Apr;12(2):83-93
pubmed: 31057694
Bioorg Chem. 2018 Oct;80:461-471
pubmed: 29986191
Appl Microbiol Biotechnol. 2022 May;106(9-10):3489-3505
pubmed: 35562490
Inflammopharmacology. 2005;13(5-6):479-84
pubmed: 16280100
Mini Rev Med Chem. 2015;15(9):762-75
pubmed: 25985954
Molecules. 2015 Dec 22;21(1):E3
pubmed: 26703554
Pharmaceuticals (Basel). 2021 Jul 11;14(7):
pubmed: 34358089
BMC Chem. 2019 Jan 28;13(1):1
pubmed: 31355363
Chem Rev. 2014 May 28;114(10):5572-610
pubmed: 24716666

Auteurs

Naresh Podila (N)

Department of Pharmaceutical Sciences, School of Biotechnology and Pharmaceutical Sciences, Vignan's Foundation for Science, Technology & Research, Vadlamudi, Guntur, 522213, Andhra Pradesh, India.

Naveen Kumar Penddinti (NK)

Vikas College of Pharmaceutical Sciences, Suryapet, Telangana, India.

Mithun Rudrapal (M)

Department of Pharmaceutical Sciences, School of Biotechnology and Pharmaceutical Sciences, Vignan's Foundation for Science, Technology & Research, Vadlamudi, Guntur, 522213, Andhra Pradesh, India.

Gourav Rakshit (G)

Department of Pharmaceutical Sciences & Technology, Birla Institute of Technology, Mesra, India, Ranchi, 835215, Jharkhand, India.

Sathish Kumar Konidala (SK)

Department of Pharmaceutical Sciences, School of Biotechnology and Pharmaceutical Sciences, Vignan's Foundation for Science, Technology & Research, Vadlamudi, Guntur, 522213, Andhra Pradesh, India.

Veera Shakar Pulusu (VS)

Ohio University, Department of Chemistry & Biochemistry, Athens, OH, USA, 45701.

Richie R Bhandare (RR)

Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, Ajman University, P O Box 346, Ajman, United Arab Emirates.
Centre of Medical and Bio-allied Health Sciences Research, Ajman University, P O Box 346, Ajman, United Arab Emirates.

Afzal B Shaik (AB)

St. Mary's College of Pharmacy, St. Mary's Group of Institutions Guntur, Affiliated to Jawaharlal Nehru Technological University Kakinada, Chebrolu, Guntur, 522212, Andhra Pradesh, India.
Center for Global Health Research, Saveetha Medical College, Saveetha Institute of Medical and Technical Sciences, India.

Classifications MeSH