Cannabis use and mood disorders: a systematic review.
bipolar disorder
cannabis
depression
major depressive disorder
mania
suicidality
Journal
Frontiers in public health
ISSN: 2296-2565
Titre abrégé: Front Public Health
Pays: Switzerland
ID NLM: 101616579
Informations de publication
Date de publication:
2024
2024
Historique:
received:
29
11
2023
accepted:
26
03
2024
medline:
24
4
2024
pubmed:
24
4
2024
entrez:
24
4
2024
Statut:
epublish
Résumé
Problematic cannabis use is highly prevalent among people with mood disorders. This underscores the need to understand the effects of cannabis and cannabinoids in this population, especially considering legalization of recreational cannabis use. We aimed to (1) systematically evaluate cross-sectional and longitudinal studies investigating the interplay between cannabis use, cannabis use disorder (CUD), and the occurrence of mood disorders and symptoms, with a focus on major depressive disorder (MDD) and bipolar disorder (BD) and; (2) examine the effects of cannabis on the prognosis and treatment outcomes of MDD and BD. Following PRISMA guidelines, we conducted an extensive search for English-language studies investigating the potential impact of cannabis on the development and prognosis of mood disorders published from inception through November 2023, using EMBASE, PsycINFO, PubMed, and MEDLINE databases. Our literature search identified 3,262 studies, with 78 meeting inclusion criteria. We found that cannabis use is associated with increased depressive and manic symptoms in the general population in addition to an elevated likelihood of developing MDD and BD. Furthermore, we observed that cannabis use is linked to an unfavorable prognosis in both MDD or BD. Our findings suggest that cannabis use may negatively influence the development, course, and prognosis of MDD and BD. Future well-designed studies, considering type, amount, and frequency of cannabis use while addressing confounding factors, are imperative for a comprehensive understanding of this relationship. https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023481634.
Sections du résumé
Background
UNASSIGNED
Problematic cannabis use is highly prevalent among people with mood disorders. This underscores the need to understand the effects of cannabis and cannabinoids in this population, especially considering legalization of recreational cannabis use.
Objectives
UNASSIGNED
We aimed to (1) systematically evaluate cross-sectional and longitudinal studies investigating the interplay between cannabis use, cannabis use disorder (CUD), and the occurrence of mood disorders and symptoms, with a focus on major depressive disorder (MDD) and bipolar disorder (BD) and; (2) examine the effects of cannabis on the prognosis and treatment outcomes of MDD and BD.
Methods
UNASSIGNED
Following PRISMA guidelines, we conducted an extensive search for English-language studies investigating the potential impact of cannabis on the development and prognosis of mood disorders published from inception through November 2023, using EMBASE, PsycINFO, PubMed, and MEDLINE databases.
Results
UNASSIGNED
Our literature search identified 3,262 studies, with 78 meeting inclusion criteria. We found that cannabis use is associated with increased depressive and manic symptoms in the general population in addition to an elevated likelihood of developing MDD and BD. Furthermore, we observed that cannabis use is linked to an unfavorable prognosis in both MDD or BD.
Discussion
UNASSIGNED
Our findings suggest that cannabis use may negatively influence the development, course, and prognosis of MDD and BD. Future well-designed studies, considering type, amount, and frequency of cannabis use while addressing confounding factors, are imperative for a comprehensive understanding of this relationship.
Systematic review registration
UNASSIGNED
https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023481634.
Identifiants
pubmed: 38655516
doi: 10.3389/fpubh.2024.1346207
pmc: PMC11035759
doi:
Types de publication
Systematic Review
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1346207Informations de copyright
Copyright © 2024 Sorkhou, Dent and George.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Addict Behav. 2011 Jul;36(7):773-6
pubmed: 21411234
J Am Acad Child Adolesc Psychiatry. 2007 Mar;46(3):408-417
pubmed: 17314727
Am J Addict. 2022 Sep;31(5):454-462
pubmed: 35690891
Ups J Med Sci. 2010 Feb;115(1):2-10
pubmed: 20187845
BMJ. 2002 Nov 23;325(7374):1195-8
pubmed: 12446533
BJPsych Open. 2021 Jul 22;7(4):e137
pubmed: 36043688
Acta Psychiatr Scand. 2016 Nov;134(5):399-409
pubmed: 27565994
Arch Gen Psychiatry. 2007 Jan;64(1):57-64
pubmed: 17199055
BMC Psychiatry. 2012 Aug 16;12:112
pubmed: 22897939
Curr Addict Rep. 2018 Sep;5(3):336-345
pubmed: 30643708
Soc Sci Med. 2019 Jul;233:181-192
pubmed: 31207470
Am J Psychiatry. 2001 Dec;158(12):2033-7
pubmed: 11729021
Prostaglandins Leukot Essent Fatty Acids. 2002 Feb-Mar;66(2-3):221-33
pubmed: 12052038
Acta Psychiatr Scand. 2008 Nov;118(5):395-403
pubmed: 18798834
J Abnorm Psychol. 2021 May;130(4):333-345
pubmed: 34180699
Eur J Neurol. 2011 Sep;18(9):1122-31
pubmed: 21362108
J Affect Disord. 2016 Nov 15;205:216-224
pubmed: 27449554
Psychiatry Res. 2013 Oct 30;209(3):459-65
pubmed: 23312479
Psychopathology. 2009;42(6):350-60
pubmed: 19752588
Lancet Psychiatry. 2017 Sep;4(9):706-714
pubmed: 28750823
Acta Psychiatr Scand. 2015 Feb;131(2):100-10
pubmed: 25430820
Biol Psychiatry. 2005 Mar 15;57(6):594-608
pubmed: 15780846
J Affect Disord. 2021 Feb 15;281:467-475
pubmed: 33360749
J Abnorm Child Psychol. 2020 Jun;48(6):771-782
pubmed: 32219606
Addict Behav. 2023 Nov;146:107809
pubmed: 37515895
Psychiatry Res. 2023 May;323:115135
pubmed: 36878177
Psychol Med. 2014 Dec;44(16):3435-44
pubmed: 25066001
PLoS Med. 2009 Jul 21;6(7):e1000097
pubmed: 19621072
Eur Neuropsychopharmacol. 2018 Jan;28(1):37-47
pubmed: 29254657
Aust N Z J Psychiatry. 2016 Jul;50(7):631-9
pubmed: 26764372
Drug Alcohol Depend. 2007 Apr;88 Suppl 1:S60-70
pubmed: 17257779
Am J Addict. 2015 Mar;24(2):105-116
pubmed: 25662704
Compr Psychiatry. 2016 Feb;65:57-62
pubmed: 26773991
Sci Rep. 2018 Feb 12;8(1):2861
pubmed: 29434331
Schizophr Res. 2011 Mar;126(1-3):270-6
pubmed: 20674280
Drug Alcohol Depend. 2013 Jun 1;130(1-3):101-8
pubmed: 23182839
Depress Anxiety. 2008;25(3):241-7
pubmed: 17345601
Nicotine Tob Res. 2023 Jul 14;25(8):1455-1464
pubmed: 37042355
J Psychiatry Neurosci. 2021 Sep;46(5):E559-E567
pubmed: 34625488
Addiction. 2019 Feb;114(2):278-293
pubmed: 30276906
J Affect Disord. 2020 Jul 1;272:98-103
pubmed: 32379627
Yale J Biol Med. 2020 Jun 29;93(2):251-264
pubmed: 32607086
Schizophr Res. 2015 Mar;162(1-3):153-61
pubmed: 25667194
Psychiatry Res. 2017 May;251:225-234
pubmed: 28214781
J Affect Disord. 2022 Feb 15;299:174-179
pubmed: 34863715
J Adolesc Health. 2014 Feb;54(2):235-40
pubmed: 24119417
BMC Public Health. 2015 Mar 10;15:233
pubmed: 25880154
J Addict Dis. 2010 Jul;29(3):325-37
pubmed: 20635282
Addiction. 2007 Aug;102(8):1251-60
pubmed: 17624975
J Pain. 2008 Mar;9(3):254-64
pubmed: 18088560
Addict Behav. 2015 Oct;49:33-9
pubmed: 26036667
J Affect Disord. 2017 Apr 15;213:168-171
pubmed: 28242498
Pharmacol Ther. 2015 Apr;148:1-16
pubmed: 25460036
Addiction. 2006 Oct;101(10):1463-72
pubmed: 16968348
J Affect Disord. 2018 Dec 1;241:8-14
pubmed: 30086434
Depress Anxiety. 2013 Jun;30(6):515-27
pubmed: 23468126
Front Neuroendocrinol. 2020 Apr;57:100841
pubmed: 32339546
Int J Drug Policy. 2018 Feb;52:87-96
pubmed: 29277082
J Child Psychol Psychiatry. 2007 Jun;48(6):592-600
pubmed: 17537075
JAMA Netw Open. 2020 Aug 3;3(8):e2013802
pubmed: 32809032
Subst Use Misuse. 2022;57(3):344-349
pubmed: 34895014
Psychiatry Res. 2021 Sep;303:114109
pubmed: 34284307
J Affect Disord. 2016 Mar 15;193:103-8
pubmed: 26773900
Biol Psychiatry. 2016 Apr 1;79(7):e17-31
pubmed: 26858212
Eur Arch Psychiatry Clin Neurosci. 2019 Feb;269(1):107-120
pubmed: 30564886
Neuropsychopharmacology. 2018 Jan;43(1):195-212
pubmed: 28853439
Am J Drug Alcohol Abuse. 2012 Nov;38(6):567-74
pubmed: 22746224
Alcohol Clin Exp Res. 2009 Jan;33(1):49-59
pubmed: 18945223
Int J Neuropsychopharmacol. 2021 Mar 17;24(3):181-190
pubmed: 33103721
PLoS One. 2015 Apr 13;10(4):e0122896
pubmed: 25875443
J Affect Disord. 2014 Dec;169 Suppl 1:S3-11
pubmed: 25533912
Schizophr Bull. 2018 Oct 17;44(6):1267-1274
pubmed: 29207008
Addict Biol. 2013 Sep;18(5):826-35
pubmed: 21967091
Front Psychiatry. 2021 Nov 15;12:767309
pubmed: 34867554
BMJ. 2019 Aug 28;366:l4898
pubmed: 31462531
J Affect Disord. 2020 Sep 1;274:1076-1083
pubmed: 32663935
Curr Opin Psychiatry. 2020 Jan;33(1):20-42
pubmed: 31714262
JAMA Psychiatry. 2019 Apr 1;76(4):426-434
pubmed: 30758486
Front Psychol. 2014 Feb 17;5:130
pubmed: 24596567
J Clin Med. 2020 Dec 23;10(1):
pubmed: 33374666
Subst Abus. 2019;40(2):178-184
pubmed: 30883274
J Consult Clin Psychol. 2019 Oct;87(10):859-871
pubmed: 31556663
Psychiatry Res. 2014 Jan 30;215(1):101-4
pubmed: 24262665
Neuroimage Clin. 2021;30:102575
pubmed: 33588323
Addiction. 2022 Aug;117(8):2264-2272
pubmed: 35315149
J Nerv Ment Dis. 2009 Jan;197(1):35-40
pubmed: 19155808
Drug Alcohol Rev. 2022 Jul;41(5):1095-1108
pubmed: 35172040
J Affect Disord. 2016 Jan 15;190:286-293
pubmed: 26544611
Early Interv Psychiatry. 2016 Feb;10(1):36-44
pubmed: 24739233
Addiction. 2023 Jun;118(6):1083-1092
pubmed: 36648021
Int J Environ Res Public Health. 2020 Jan 14;17(2):
pubmed: 31947505
Can J Psychiatry. 2020 Feb;65(2):115-123
pubmed: 31177831
Addict Behav. 2010 Jun;35(6):644-6
pubmed: 20189314
Psychol Med. 2014 Mar;44(4):797-810
pubmed: 23795762
Psychol Med. 2018 Oct;48(13):2169-2176
pubmed: 29607801
JAMA Psychiatry. 2020 Oct 1;77(10):1044-1051
pubmed: 32459328
Drug Alcohol Depend. 2020 Nov 1;216:108332
pubmed: 33080503
J Affect Disord. 2018 Jul;234:327-334
pubmed: 29605793
J Affect Disord. 2015 Feb 1;172:211-8
pubmed: 25451420
J Psychopharmacol. 2023 Sep;37(9):920-927
pubmed: 37497695
J Stud Alcohol Drugs. 2016 Mar;77(2):287-97
pubmed: 26997187
Psychol Addict Behav. 2008 Jun;22(2):186-97
pubmed: 18540716
Neurosci Lett. 2012 Mar 9;511(2):89-94
pubmed: 22306089
J Clin Psychiatry. 2018 Jun 5;79(4):
pubmed: 29877641
J Int Neuropsychol Soc. 2007 Sep;13(5):807-20
pubmed: 17697412
Bipolar Disord. 2008 Sep;10(6):738-41
pubmed: 18837869
Ment Health Subst Use. 2012;5(3):228-239
pubmed: 35444716
J Affect Disord. 2006 Oct;95(1-3):103-10
pubmed: 16793142
Psychiatry Res. 2011 Feb 28;185(3):459-61
pubmed: 20674039
J Affect Disord. 2012 Apr;138(1-2):54-62
pubmed: 22310034
Can J Psychiatry. 2023 May;68(5):299-311
pubmed: 35711159
Eur Arch Psychiatry Clin Neurosci. 2011 Sep;261(6):397-405
pubmed: 21267743
Br J Psychiatry. 2001 Feb;178:101-6
pubmed: 11157422