Organ Neuroprosthetics: Connecting Transplanted and Artificial Organs with the Nervous System.

bioelectronic medicine internal organs neuroprosthetics

Journal

Advanced healthcare materials
ISSN: 2192-2659
Titre abrégé: Adv Healthc Mater
Pays: Germany
ID NLM: 101581613

Informations de publication

Date de publication:
24 Apr 2024
Historique:
revised: 01 04 2024
received: 30 08 2023
medline: 24 4 2024
pubmed: 24 4 2024
entrez: 24 4 2024
Statut: aheadofprint

Résumé

Implantable neural interfaces with the central and peripheral nervous systems are currently used to restore sensory, motor, and cognitive functions in disabled people with very promising results. They have also been used to modulate autonomic activities to treat diseases such as diabetes or hypertension. Here, this study proposes to extend the use of these technologies to (re-)establish the connection between new (transplanted or artificial) organs and the nervous system in order to increase the long-term efficacy and the effective biointegration of these solutions. In this perspective paper, some clinically relevant applications of this approach are briefly described. Then, the choices that neural engineers must implement about the type, implantation location, and closed-loop control algorithms to successfully realize this approach are highlighted. It is believed that these new "organ neuroprostheses" are going to become more and more valuable and very effective solutions in the years to come.

Identifiants

pubmed: 38656615
doi: 10.1002/adhm.202302896
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2302896

Subventions

Organisme : HORIZON EUROPE Framework Programme
Organisme : Fondation Bertarelli donation
Organisme : Horizon 2020 FET project: NeuHeart project http://www.neuhearth2020.eu/ Project PR19-CR-P2 - BioSUP funded by INAIL (Italian Institute for Disabled Workers)

Informations de copyright

© 2024 The Authors. Advanced Healthcare Materials published by Wiley‐VCH GmbH.

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Auteurs

Silvestro Micera (S)

The BioRobotics Institute and Department of Excellence in Robotics and AI, Scuola Superiore Sant'Anna, Pisa, 56127, Italy.
Interdisciplinary Research Center Health Science, Scuola Superiore Sant'Anna, Pisa, 56127, Italy.
Bertarelli Foundation Chair in Translational Neuroengineering, Neuro-X Institute, School of Engineering, Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne, 1015, Switzerland.

Arianna Menciassi (A)

The BioRobotics Institute and Department of Excellence in Robotics and AI, Scuola Superiore Sant'Anna, Pisa, 56127, Italy.
Interdisciplinary Research Center Health Science, Scuola Superiore Sant'Anna, Pisa, 56127, Italy.

Luisella Cianferotti (L)

Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, 50121, Italy.

Emanuele Gruppioni (E)

Centro Protesi INAIL, Budrio, 40054, Italy.

Vincenzo Lionetti (V)

Interdisciplinary Research Center Health Science, Scuola Superiore Sant'Anna, Pisa, 56127, Italy.
UOSVD Anesthesia and Resuscitation, Fondazione Toscana G. Monasterio, Pisa, 56127, Italy.

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