Participant perspectives on incentives for TB preventative therapy adherence and reduced alcohol use: A qualitative study.


Journal

PLOS global public health
ISSN: 2767-3375
Titre abrégé: PLOS Glob Public Health
Pays: United States
ID NLM: 9918283779606676

Informations de publication

Date de publication:
2024
Historique:
received: 05 05 2023
accepted: 20 02 2024
medline: 24 4 2024
pubmed: 24 4 2024
entrez: 24 4 2024
Statut: epublish

Résumé

Economic incentives to promote health behavior change are highly efficacious for substance use disorders as well as increased medication adherence. Knowledge about participants' experiences with and perceptions of incentives is needed to understand their mechanisms of action and optimize future incentive-based interventions. The Drinkers' Intervention to Prevent Tuberculosis (DIPT) trial enrolled people with HIV (PWH) in Uganda with latent tuberculosis and unhealthy alcohol use in a 2x2 factorial trial that incentivized recent alcohol abstinence and isoniazid (INH) adherence on monthly urine testing while on INH preventive therapy. We interviewed 32 DIPT study participants across trial arms to explore their perspectives on this intervention. Participants described 1) satisfaction with incentives of sufficient size that allowed them to purchase items that improved their quality of life, 2) multiple ways in which incentives were motivating, from gamification of "winning" through support of pre-existing desire to improve health to suggesting variable effects of extrinsic and intrinsic motivation, and 3) finding value in learning results of increased clinical monitoring. To build effective incentive programs to support both reduced substance use and increased antimicrobial adherence, we recommend carefully selecting incentive magnitude as well as harnessing both intrinsic motivation to improve health and extrinsic reward of target behavior. In addition to these participant-described strengths, incorporating results of clinical monitoring related to the incentive program that provide participants more information about their health may also contribute to health-related empowerment.

Identifiants

pubmed: 38656992
doi: 10.1371/journal.pgph.0002472
pii: PGPH-D-23-00821
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e0002472

Informations de copyright

Copyright: © 2024 Appa et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Auteurs

Ayesha Appa (A)

Department of Medicine, University of California San Francisco, San Francisco, California, United States of America.

Amanda P Miller (AP)

School of Public Health, San Diego State University, San Diego, California, United States of America.

Robin Fatch (R)

Department of Medicine, University of California San Francisco, San Francisco, California, United States of America.

Allen Kekibiina (A)

Global Health Collaborative, Mbarara University of Science and Technology, Mbarara, Uganda.

Brian Beesiga (B)

Infectious Diseases Research Collaboration (IDRC), Kampala, Uganda.

Julian Adong (J)

Global Health Collaborative, Mbarara University of Science and Technology, Mbarara, Uganda.

Nneka Emenyonu (N)

Department of Medicine, University of California San Francisco, San Francisco, California, United States of America.

Kara Marson (K)

Department of Medicine, University of California San Francisco, San Francisco, California, United States of America.

Monica Getahun (M)

Institute for Global Health Sciences, University of California San Francisco, San Francisco, California, United States of America.

Moses Kamya (M)

Infectious Diseases Research Collaboration (IDRC), Kampala, Uganda.

Winnie Muyindike (W)

Global Health Collaborative, Mbarara University of Science and Technology, Mbarara, Uganda.

Michael McDonell (M)

Department of Psychiatry and Behavioral Sciences, Washington State University, Spokane, Washington, United States of America.

Harsha Thirumurthy (H)

Department of Medical Ethics and Health Policy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

Judith A Hahn (JA)

Department of Medicine, University of California San Francisco, San Francisco, California, United States of America.

Gabriel Chamie (G)

Department of Medicine, University of California San Francisco, San Francisco, California, United States of America.

Carol S Camlin (CS)

Department of Obstetrics, Gynecology & Reproductive Sciences, University of California San Francisco, San Francisco, California, United States of America.

Classifications MeSH