Percutaneous endoscopic lumbar discectomy combined with platelet-rich plasma injection for lumbar disc herniation: analysis of clinical and imaging outcomes.
Humans
Platelet-Rich Plasma
Intervertebral Disc Displacement
/ surgery
Male
Female
Lumbar Vertebrae
/ surgery
Diskectomy, Percutaneous
/ methods
Retrospective Studies
Adult
Middle Aged
Treatment Outcome
Endoscopy
/ methods
Pain Measurement
Combined Modality Therapy
/ methods
Magnetic Resonance Imaging
Disc degeneration
Lumbar disc herniation
Percutaneous endoscopic lumbar discectomy
Platelet-rich plasma
Repair
Journal
BMC musculoskeletal disorders
ISSN: 1471-2474
Titre abrégé: BMC Musculoskelet Disord
Pays: England
ID NLM: 100968565
Informations de publication
Date de publication:
24 Apr 2024
24 Apr 2024
Historique:
received:
15
01
2024
accepted:
15
04
2024
medline:
25
4
2024
pubmed:
25
4
2024
entrez:
24
4
2024
Statut:
epublish
Résumé
To evaluate the clinical efficacy and imaging outcomes of percutaneous endoscopic lumbar discectomy (PELD) combined with platelet-rich plasma (PRP) for the treatment of lumbar disc herniation (LDH). A total of 155 patients with LDH between January 2020 and June 2022 were retrospective analyzed, of which 75 underwent PELD with PRP and 80 underwent PELD only. Clinical functional scores and imaging data were compared. Clinical functional scores included visual analog scale of leg pain (VAS-LP) and back pain (VAS-BP), Japanese Orthopedic Association score (JOA), Oswestry Disability Index (ODI) and modified MacNab criteria. Imaging data included disc height index (DHI), spinal cross-sectional area (SCSA), disc protrusion size (DPZ), and ratio value of disc grey scales (RVG). Both groups showed clinical improvement, and VAS-LP, VAS-BP, JOA and ODI were significantly improved in the PRP group compared with the control group at 3, 6 and 12 months postoperatively (P < 0.05). At the last follow-up, the differences in SCSA, DPZ and RVG between the two groups were statistically significant (P < 0.05), with the PRP group being superior to the control group. The excellent and good rates of the modified Macnab criteria in the PRP group and control group were 93.3% and 90%, respectively, with no statistically significant difference (P > 0.05). No serious complications occurred during the follow-up period. PELD combined with PRP is a safe and effective method for treating patients with LDH. PRP injection was beneficial for delaying disc degeneration and promoting disc remodeling.
Identifiants
pubmed: 38658984
doi: 10.1186/s12891-024-07444-8
pii: 10.1186/s12891-024-07444-8
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
328Subventions
Organisme : Research and Demonstration application of Clinical Diagnosis and Treatment Technology in Beijing
ID : Z191100006619028
Organisme : Research and Demonstration application of Clinical Diagnosis and Treatment Technology in Beijing
ID : Z191100006619028
Organisme : Research and Demonstration application of Clinical Diagnosis and Treatment Technology in Beijing
ID : Z191100006619028
Organisme : Research and Demonstration application of Clinical Diagnosis and Treatment Technology in Beijing
ID : Z191100006619028
Organisme : Research and Demonstration application of Clinical Diagnosis and Treatment Technology in Beijing
ID : Z191100006619028
Informations de copyright
© 2024. The Author(s).
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