Novel mass spectrometry-based assay for thymidylate synthase activity.
5-fluorouracil
enzyme activity assay
liquid chromatography–mass spectrometry
thymidylate synthase
Journal
Nucleosides, nucleotides & nucleic acids
ISSN: 1532-2335
Titre abrégé: Nucleosides Nucleotides Nucleic Acids
Pays: United States
ID NLM: 100892832
Informations de publication
Date de publication:
25 Apr 2024
25 Apr 2024
Historique:
medline:
25
4
2024
pubmed:
25
4
2024
entrez:
25
4
2024
Statut:
aheadofprint
Résumé
Thymidylate synthase (TS) is an enzyme responsible for the conversion of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), with the co-substrate 5,10-methylenetetrahydrofolate (5,10-CH
Identifiants
pubmed: 38660992
doi: 10.1080/15257770.2024.2344187
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM