Nanogels Based on N,N-Dimethylacrylamide and β-Cyclodextrin Triacrylate for Enhanced Solubility and Therapeutic Efficacy of Aripiprazole.
antipsychotic drugs delivery
aripiprazole
drug delivery systems
nanogel
nanoparticles
Journal
Gels (Basel, Switzerland)
ISSN: 2310-2861
Titre abrégé: Gels
Pays: Switzerland
ID NLM: 101696925
Informations de publication
Date de publication:
22 Mar 2024
22 Mar 2024
Historique:
received:
29
02
2024
revised:
14
03
2024
accepted:
20
03
2024
medline:
26
4
2024
pubmed:
26
4
2024
entrez:
26
4
2024
Statut:
epublish
Résumé
Aripiprazole (ARZ) is a medication used for the treatment of various diseases such as schizophrenia, bipolar disorder, major depressive disorder, autism, and Tourette's syndrome. Despite its therapeutic benefits, ARZ is characterized by a poor water solubility which provoked the development of various delivery systems in order to enhance its solubility. In the present work, a nanoscale drug delivery system based on N,N-dimethylacrylamide (DMAA) and β-cyclodextrin triacrylate (β-CD-Ac
Identifiants
pubmed: 38667636
pii: gels10040217
doi: 10.3390/gels10040217
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : European Union-NextGenerationEU, through the National Recovery and Resilience Plan of the Republic of Bulgaria
ID : BG-RRP-2.004-0004-C01