Design, Synthesis, and Investigation of the Pharmacokinetics and Anticancer Activities of Indenoisoquinoline Derivatives That Stabilize the G-Quadruplex in the

Journal

Journal of medicinal chemistry
ISSN: 1520-4804
Titre abrégé: J Med Chem
Pays: United States
ID NLM: 9716531

Informations de publication

Date de publication:
26 Apr 2024
Historique:
medline: 26 4 2024
pubmed: 26 4 2024
entrez: 26 4 2024
Statut: aheadofprint

Résumé

G-quadruplexes are noncanonical four-stranded DNA secondary structures.

Identifiants

DOI: 10.1021/acs.jmedchem.3c02303 PMID: 38668707
pubmed: 38668707
doi: 10.1021/acs.jmedchem.3c02303
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Yichen Han (Y)

Borch Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana 47907, United States.
ORCID: 0000-0002-1034-2958

Adam Buric (A)

Borch Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana 47907, United States.

Venkat Chintareddy (V)

Therachem Research Medilab LLC, 100 Jade Park, Chelsea, Alabama 35043, United States.

Mercedes DeMoss (M)

Borch Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana 47907, United States.

Luying Chen (L)

Borch Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana 47907, United States.

Jonathan Dickerhoff (J)

Borch Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana 47907, United States.
ORCID: 0000-0002-3197-9472

Robyn De Dios (R)

Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States.

Pooran Chand (P)

Therachem Research Medilab LLC, 100 Jade Park, Chelsea, Alabama 35043, United States.

Randall Riggs (R)

Gibson Oncology, 7772 Fisher Island Drive, Miami, Florida 33109, United States.

Danzhou Yang (D)

Borch Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana 47907, United States.
Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States.
Purdue Institute for Cancer Research, Purdue University, West Lafayette, Indiana 47907, United States.
ORCID: 0000-0001-7489-7111

Mark Cushman (M)

Borch Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana 47907, United States.
Purdue Institute for Cancer Research, Purdue University, West Lafayette, Indiana 47907, United States.
ORCID: 0000-0002-0152-5891

Classifications MeSH