Nrf2 Plays a Key Role in Erythropoiesis during Aging.

ATF6 GADD34 PLGA UPR system astaxanthin autophagy ineffective erythropoiesis nanoparticles oxidation red cells

Journal

Antioxidants (Basel, Switzerland)
ISSN: 2076-3921
Titre abrégé: Antioxidants (Basel)
Pays: Switzerland
ID NLM: 101668981

Informations de publication

Date de publication:
12 Apr 2024
Historique:
received: 15 03 2024
revised: 06 04 2024
accepted: 08 04 2024
medline: 27 4 2024
pubmed: 27 4 2024
entrez: 27 4 2024
Statut: epublish

Résumé

Aging is characterized by increased oxidation and reduced efficiency of cytoprotective mechanisms. Nuclear factor erythroid-2-related factor (Nrf2) is a key transcription factor, controlling the expression of multiple antioxidant proteins. Here, we show that Nrf2

Identifiants

DOI: 10.3390/antiox13040454 PMID: 38671902
pubmed: 38671902
pii: antiox13040454
doi: 10.3390/antiox13040454
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Ministero dell'Istruzione e del Merito
ID : 2020Z22PM7

Auteurs

Serge Cedrick Toya Mbiandjeu (SCT)

Department of Medicine, University of Verona, 37134 Verona, Italy.

Angela Siciliano (A)

Dipartimento Ingegneria per la Medicina di Innovazione-DIMI, University of Verona, 37134 Verona, Italy.
Department of Medicine, AOUI Verona, 37134 Verona, Italy.

Alessandro Mattè (A)

Department of Medicine, University of Verona, 37134 Verona, Italy.

Enrica Federti (E)

Dipartimento Ingegneria per la Medicina di Innovazione-DIMI, University of Verona, 37134 Verona, Italy.
Department of Medicine, AOUI Verona, 37134 Verona, Italy.

Massimiliano Perduca (M)

Department of Biotechnology, University of Verona, 37134 Verona, Italy.
ORCID: 0000-0001-8291-0523

Davide Melisi (D)

Department of Medicine, University of Verona, 37134 Verona, Italy.
ORCID: 0000-0002-4031-7585

Immacolata Andolfo (I)

Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, 80131 Naples, Italy.
CEINGE Biotecnologie Avanzate, 80131 Naples, Italy.

Angela Amoresano (A)

Department of Chimical Sciences, University Federico II, 80138 Naples, Italy.

Achille Iolascon (A)

Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, 80131 Naples, Italy.
CEINGE Biotecnologie Avanzate, 80131 Naples, Italy.
ORCID: 0000-0002-9558-0356

Maria Teresa Valenti (MT)

Department of Neuroscience, University of Verona, 37134 Verona, Italy.
ORCID: 0000-0003-1166-8033

Francesco Turrini (F)

Department of Oncology, University of Torino, 10124 Torino, Italy.

Michele Bovi (M)

Department of Biotechnology, University of Verona, 37134 Verona, Italy.

Arianna Pisani (A)

Department of Biotechnology, University of Verona, 37134 Verona, Italy.

Antonio Recchiuti (A)

Department of Medical, Oral, and Biotechnology Science, "G. d'Annunzio" University Chieti-Pescara, 66013 Chieti, Italy.
ORCID: 0000-0002-1409-5261

Domenico Mattoscio (D)

Department of Medical, Oral, and Biotechnology Science, "G. d'Annunzio" University Chieti-Pescara, 66013 Chieti, Italy.
ORCID: 0000-0002-2149-2855

Veronica Riccardi (V)

Dipartimento Ingegneria per la Medicina di Innovazione-DIMI, University of Verona, 37134 Verona, Italy.

Luca Dalle Carbonare (L)

Dipartimento Ingegneria per la Medicina di Innovazione-DIMI, University of Verona, 37134 Verona, Italy.
Department of Medicine, AOUI Verona, 37134 Verona, Italy.
ORCID: 0000-0003-3263-6671

Carlo Brugnara (C)

Department of Laboratory Medicine, Boston Children's Hospital, Boston, MA 02114, USA.
Department of Pathology, Harvard Medical School, Boston, MA 02114, USA.

Narla Mohandas (N)

New York Blood Center Enterprises, New York, NY 10065, USA.

Lucia De Franceschi (L)

Dipartimento Ingegneria per la Medicina di Innovazione-DIMI, University of Verona, 37134 Verona, Italy.
Department of Medicine, AOUI Verona, 37134 Verona, Italy.
ORCID: 0000-0001-7093-777X

Classifications MeSH