Predicting Isocitrate Dehydrogenase Status in Non-Contrast-Enhanced Adult-Type Astrocytic Tumors Using Diffusion Tensor Imaging and

astrocytoma diffusion tensor imaging glioblastoma glioma isocitrate dehydrogenase mutation positron emission tomography

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
18 Apr 2024
Historique:
received: 02 04 2024
revised: 16 04 2024
accepted: 16 04 2024
medline: 27 4 2024
pubmed: 27 4 2024
entrez: 27 4 2024
Statut: epublish

Résumé

We aimed to differentiate the isocitrate dehydrogenase (IDH) status among non-enhanced astrocytic tumors using preoperative MRI and PET. We analyzed 82 patients with non-contrast-enhanced, diffuse, supratentorial astrocytic tumors (IDH mutant [IDH-mut], 55 patients; IDH-wildtype [IDH-wt], 27 patients) who underwent MRI and PET between May 2012 and December 2022. We calculated the fractional anisotropy (FA) and mean diffusivity (MD) values using diffusion tensor imaging. We evaluated the tumor/normal brain uptake (T/N) ratios using

Identifiants

DOI: 10.3390/cancers16081543 PMID: 38672625
pubmed: 38672625
pii: cancers16081543
doi: 10.3390/cancers16081543
pii:
doi:

Types de publication

Journal Article

Langues

eng

Auteurs

Shoji Yasuda (S)

Department of Neurosurgery, Chubu Medical Center for Prolonged Traumatic Brain Dysfunction, Minokamo 505-0034, Japan.
Department of Neurosurgery, Chubu Neurorehabilitation Hospital, Minokamo 505-0034, Japan.
Department of Neurosurgery, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.
ORCID: 0009-0001-7191-4841

Hirohito Yano (H)

Department of Neurosurgery, Chubu Medical Center for Prolonged Traumatic Brain Dysfunction, Minokamo 505-0034, Japan.
Department of Neurosurgery, Chubu Neurorehabilitation Hospital, Minokamo 505-0034, Japan.
Department of Clinical Brain Sciences, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.
ORCID: 0000-0002-4252-4780

Yuka Ikegame (Y)

Department of Neurosurgery, Chubu Medical Center for Prolonged Traumatic Brain Dysfunction, Minokamo 505-0034, Japan.
Department of Neurosurgery, Chubu Neurorehabilitation Hospital, Minokamo 505-0034, Japan.
ORCID: 0000-0002-8932-9798

Soko Ikuta (S)

Department of Neurosurgery, Tokyo Women's Medical University, Tokyo 162-8666, Japan.

Takashi Maruyama (T)

Department of Neurosurgery, Tokyo Women's Medical University, Tokyo 162-8666, Japan.

Morio Kumagai (M)

Department of Neurosurgery, Chubu Medical Center for Prolonged Traumatic Brain Dysfunction, Minokamo 505-0034, Japan.
Department of Neurosurgery, Chubu Neurorehabilitation Hospital, Minokamo 505-0034, Japan.

Yoshihiro Muragaki (Y)

Department of Neurosurgery, Tokyo Women's Medical University, Tokyo 162-8666, Japan.

Toru Iwama (T)

Department of Neurosurgery, Gifu Municipal Hospital, Gifu 500-8513, Japan.
ORCID: 0000-0002-9426-284X

Jun Shinoda (J)

Department of Neurosurgery, Chubu Medical Center for Prolonged Traumatic Brain Dysfunction, Minokamo 505-0034, Japan.
Department of Neurosurgery, Chubu Neurorehabilitation Hospital, Minokamo 505-0034, Japan.
Department of Clinical Brain Sciences, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.

Tsuyoshi Izumo (T)

Department of Neurosurgery, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan.
ORCID: 0000-0001-8778-2698

Classifications MeSH