Confronting a New Challenge in Plastic Surgery: MDR Infections in Patients with Chronic Wounds.

MDR infections chronic wounds diabetes diabetic foot ulcers ulcers

Journal

Life (Basel, Switzerland)
ISSN: 2075-1729
Titre abrégé: Life (Basel)
Pays: Switzerland
ID NLM: 101580444

Informations de publication

Date de publication:
27 Mar 2024
Historique:
received: 02 02 2024
revised: 20 03 2024
accepted: 25 03 2024
medline: 27 4 2024
pubmed: 27 4 2024
entrez: 27 4 2024
Statut: epublish

Résumé

The presence of a wound can be anywhere from non-problematic to life-threatening on a severity spectrum, with bacterial infection and resistance playing a major role in the development of chronicity, delaying wound healing. Wound colonization with multiple organisms and the limited number of effective antibiotics place a heavy burden on the healthcare system, with patients going through multiple surgeries during a prolonged hospitalization time. By analyzing the resistance patterns of pluri-bacterial populations and the approach used in managing complex cases, we aim to improve the protocols applied in caring for chronic wounds in our practice and share our experiences and observations. We designed a retrospective study on 212 diabetic and non-diabetic patients, aiming to evaluate the course of chronic wound treatment in our practice. We focused on the impact that MDR bacteria and diabetes have on surgical outcomes and their role in the healing process. Patients who received empiric antibiotic therapy before being admitted eventually presented with multiple MDR bacteria compared to those who did not receive antibiotics ( Proper management of chronic wounds requires a comprehensive, multidisciplinary approach and a thorough understanding of antibiotic usage. To address this need, we have developed and implemented a chronic wound treatment protocol in our clinic, with the goal of discharging patients once their ulcers have been treated and closed. A key summary of the protocol presented is to reduce the incidence of MDR bacteria and improve the patient's quality of life.

Sections du résumé

BACKGROUND BACKGROUND
The presence of a wound can be anywhere from non-problematic to life-threatening on a severity spectrum, with bacterial infection and resistance playing a major role in the development of chronicity, delaying wound healing. Wound colonization with multiple organisms and the limited number of effective antibiotics place a heavy burden on the healthcare system, with patients going through multiple surgeries during a prolonged hospitalization time. By analyzing the resistance patterns of pluri-bacterial populations and the approach used in managing complex cases, we aim to improve the protocols applied in caring for chronic wounds in our practice and share our experiences and observations.
METHODS METHODS
We designed a retrospective study on 212 diabetic and non-diabetic patients, aiming to evaluate the course of chronic wound treatment in our practice. We focused on the impact that MDR bacteria and diabetes have on surgical outcomes and their role in the healing process.
RESULTS RESULTS
Patients who received empiric antibiotic therapy before being admitted eventually presented with multiple MDR bacteria compared to those who did not receive antibiotics (
CONCLUSIONS CONCLUSIONS
Proper management of chronic wounds requires a comprehensive, multidisciplinary approach and a thorough understanding of antibiotic usage. To address this need, we have developed and implemented a chronic wound treatment protocol in our clinic, with the goal of discharging patients once their ulcers have been treated and closed. A key summary of the protocol presented is to reduce the incidence of MDR bacteria and improve the patient's quality of life.

Identifiants

pubmed: 38672715
pii: life14040444
doi: 10.3390/life14040444
pii:
doi:

Types de publication

Journal Article

Langues

eng

Auteurs

Laura Răducu (L)

Discipline of Plastic Surgery, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Department of Plastic and Reconstructive Surgery, "Prof. Dr. Agrippa Ionescu" Emergency Clinical Hospital, 011356 Bucharest, Romania.

Oriana Elena Moraru (OE)

Discipline of Cardiovascular Surgery, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Department of Vascular Surgery, "Prof. Dr. Agrippa Ionescu" Emergency Clinical Hospital, 011356 Bucharest, Romania.

Daniela-Elena Gheoca-Mutu (DE)

Department of Plastic and Reconstructive Surgery, "Prof. Dr. Agrippa Ionescu" Emergency Clinical Hospital, 011356 Bucharest, Romania.
Discipline of Anatomy, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Teodora Peligrad (T)

Department of Plastic and Reconstructive Surgery, "Prof. Dr. Agrippa Ionescu" Emergency Clinical Hospital, 011356 Bucharest, Romania.

Andrada-Elena Țigăran (AE)

Department of Plastic and Reconstructive Surgery, "Prof. Dr. Agrippa Ionescu" Emergency Clinical Hospital, 011356 Bucharest, Romania.

Abdalah Abu-Baker (A)

Department of Plastic and Reconstructive Surgery, "Prof. Dr. Agrippa Ionescu" Emergency Clinical Hospital, 011356 Bucharest, Romania.
Doctoral School, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Daniela-Elena Ion (DE)

Department of Plastic and Reconstructive Surgery, "Prof. Dr. Agrippa Ionescu" Emergency Clinical Hospital, 011356 Bucharest, Romania.

Bogdan Mihai Ursuț (BM)

Discipline of Anatomy, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Department of General Surgery, "Prof. Dr. Agrippa Ionescu" Emergency Clinical Hospital, 011356 Bucharest, Romania.

Cristian-Radu Jecan (CR)

Discipline of Plastic Surgery, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Department of Plastic and Reconstructive Surgery, "Prof. Dr. Agrippa Ionescu" Emergency Clinical Hospital, 011356 Bucharest, Romania.

Adelaida Avino (A)

Discipline of Plastic Surgery, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Department of Plastic and Reconstructive Surgery, "Prof. Dr. Agrippa Ionescu" Emergency Clinical Hospital, 011356 Bucharest, Romania.
Doctoral School, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Classifications MeSH