Feasibility and Preliminary Efficacy of American Elderberry Juice for Improving Cognition and Inflammation in Patients with Mild Cognitive Impairment.

Humans Cognitive Dysfunction Male Aged Female Fruit and Vegetable Juices Cognition / drug effects Inflammation / blood Double-Blind Method Sambucus / chemistry Aged, 80 and over Biomarkers / blood Feasibility Studies Sambucus nigra / chemistry
cognition elderberry inflammatory mild cognitive impairment proteomics sambucus

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
15 Apr 2024
Historique:
received: 06 03 2024
revised: 28 03 2024
accepted: 10 04 2024
medline: 27 4 2024
pubmed: 27 4 2024
entrez: 27 4 2024
Statut: epublish

Résumé

Despite data showing that nutritional interventions high in antioxidant/anti-inflammatory properties (anthocyanin-rich foods, such as blueberries/elderberries) may decrease risk of memory loss and cognitive decline, evidence for such effects in mild cognitive impairment (MCI) is limited. This study examined preliminary effects of American elderberry (Sambucus nigra subsp. canadensis) juice on cognition and inflammatory markers in patients with MCI. In a randomized, double-blind, placebo-controlled trial, patients with MCI (

Identifiants

DOI: 10.3390/ijms25084352 PMID: 38673938
pubmed: 38673938
pii: ijms25084352
doi: 10.3390/ijms25084352
pii:
doi:

Substances chimiques

Biomarkers 0

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Mizzou Advantage Grant
ID : N/A

Auteurs

Ashley F Curtis (AF)

College of Nursing, University of South Florida, Tampa, FL 33620, USA.
ORCID: 0000-0002-2311-5674

Madison Musich (M)

Department of Psychological Sciences, University of Missouri, Columbia, MO 65201, USA.
ORCID: 0000-0002-0811-1878

Amy N Costa (AN)

College of Nursing, University of South Florida, Tampa, FL 33620, USA.
Department of Psychology, University of South Florida, Tampa, FL 33620, USA.
ORCID: 0000-0001-8863-3352

Joshua Gonzales (J)

School of Osteopathic Medicine, A. T. Still University, Kirksville, MO 63501, USA.
Department of Internal Medicine, School of Medicine, Indiana University, Indianapolis, IN 46202, USA.

Hyeri Gonzales (H)

School of Medicine, University of Missouri, Columbia, MO 65211, USA.

Bradley J Ferguson (BJ)

Department of Neurology, University of Missouri, Columbia, MO 65211, USA.
ORCID: 0000-0002-1636-7849

Briana Kille (B)

Department of Psychological Sciences, University of Missouri, Columbia, MO 65201, USA.
Children's Hospital Colorado, Aurora, CO 80045, USA.

Andrew L Thomas (AL)

Division of Plant Science and Technology, University of Missouri, Southwest Research Extension and Education Center, Mt. Vernon, MO 65201, USA.

Xing Wei (X)

Charles W. Gehrke Proteomics Center, Department of Chemistry, University of Missouri, Columbia, MO 65201, USA.

Pei Liu (P)

Charles W. Gehrke Proteomics Center, Department of Chemistry, University of Missouri, Columbia, MO 65201, USA.

C Michael Greenlief (CM)

Charles W. Gehrke Proteomics Center, Department of Chemistry, University of Missouri, Columbia, MO 65201, USA.
ORCID: 0000-0001-6420-7375

Joel I Shenker (JI)

Department of Neurology, University of Missouri, Columbia, MO 65211, USA.

David Q Beversdorf (DQ)

Department of Psychological Sciences, University of Missouri, Columbia, MO 65201, USA.
Department of Neurology, University of Missouri, Columbia, MO 65211, USA.
Department of Radiology, University of Missouri, Columbia, MO 65211, USA.
ORCID: 0000-0002-0298-0634

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Feasibility and Preliminary Efficacy of...
questionsmedicales.fr › Troubles mentaux › Troubles neurocognitifs › Troubles de la cognition › Dysfonctionnement cognitif › Feasibility and Preliminary Efficacy of...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Feasibility and Preliminary Efficacy of...
questionsmedicales.fr › Aliments et boissons › Boissons › Jus de fruits et de légumes › Feasibility and Preliminary Efficacy of...
questionsmedicales.fr › Phénomènes psychologiques › Processus mentaux › Cognition › Feasibility and Preliminary Efficacy of...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Inflammation › Feasibility and Preliminary Efficacy of...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Méthodologie en recherche épidémiologique › Méthode en double aveugle › Feasibility and Preliminary Efficacy of...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Dipsacales › Adoxaceae › Sambucus › Feasibility and Preliminary Efficacy of...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Sujet âgé de 80 ans ou plus › Feasibility and Preliminary Efficacy of...
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Feasibility and Preliminary Efficacy of...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études de faisabilité › Feasibility and Preliminary Efficacy of...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Dipsacales › Adoxaceae › Sambucus › Sambucus nigra › Feasibility and Preliminary Efficacy of...