Exploring the antileishmanial activity of dicentrine from Ocotea puberula (Lauraceae) using biomembrane models.
Alkaloid
Antiprotozoal
BAM
Langmuir films
Monolayers
PM-IRRAS
Journal
Bioorganic chemistry
ISSN: 1090-2120
Titre abrégé: Bioorg Chem
Pays: United States
ID NLM: 1303703
Informations de publication
Date de publication:
27 Apr 2024
27 Apr 2024
Historique:
received:
13
12
2023
revised:
08
03
2024
accepted:
26
04
2024
medline:
29
4
2024
pubmed:
29
4
2024
entrez:
28
4
2024
Statut:
aheadofprint
Résumé
This study aimed to assess the antiprotozoal efficacy of dicentrine, an aporphine alkaloid isolated from Ocotea puberula, against amastigote forms of Leishmania (L.) infantum. Our findings reveal that dicentrine demonstrated a notable EC
Identifiants
pubmed: 38678776
pii: S0045-2068(24)00313-4
doi: 10.1016/j.bioorg.2024.107408
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
107408Informations de copyright
Copyright © 2024 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.