Hematological, biochemical, and histopathological evaluation of the
Acute toxicity
Biochemistry
Hematology
Histopathology
Morus alba
Journal
Open veterinary journal
ISSN: 2218-6050
Titre abrégé: Open Vet J
Pays: Libya
ID NLM: 101653182
Informations de publication
Date de publication:
Mar 2024
Mar 2024
Historique:
received:
17
08
2023
accepted:
07
02
2024
medline:
29
4
2024
pubmed:
29
4
2024
entrez:
29
4
2024
Statut:
ppublish
Résumé
Studies have reported that the phytochemical content of Mulberry ( This study investigated In particular, this study utilized 12 female Institute of Cancer Research mice, 8 weeks old, divided into 2 groups: the control group and the MAE group (2,000 mg/kg single dose). Physiology, hematology, biochemistry, and histology were analyzed during the study. The examination result indicated no mortality and behavioral changes throughout the testing period. However, the mice developed mild anemia and leukopenia, followed by decreased numbers of neutrophils, lymphocytes, and monocytes. In addition, the mice developed a mild hepatocellular injury, indicated by significant ( It was evident that a single oral administration of MAE was not lethal for mice (LD
Sections du résumé
Background
UNASSIGNED
Studies have reported that the phytochemical content of Mulberry (
Aim
UNASSIGNED
This study investigated
Methods
UNASSIGNED
In particular, this study utilized 12 female Institute of Cancer Research mice, 8 weeks old, divided into 2 groups: the control group and the MAE group (2,000 mg/kg single dose). Physiology, hematology, biochemistry, and histology were analyzed during the study.
Results
UNASSIGNED
The examination result indicated no mortality and behavioral changes throughout the testing period. However, the mice developed mild anemia and leukopenia, followed by decreased numbers of neutrophils, lymphocytes, and monocytes. In addition, the mice developed a mild hepatocellular injury, indicated by significant (
Conclusion
UNASSIGNED
It was evident that a single oral administration of MAE was not lethal for mice (LD
Identifiants
pubmed: 38682142
doi: 10.5455/OVJ.2024.v14.i3.1
pii: OVJ-14-750
pmc: PMC11052622
doi:
Substances chimiques
Plant Extracts
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
750-758Déclaration de conflit d'intérêts
The authors declare that there is no conflict of interest.