Characterizing Important Dietary Exposure Sources of Perfluoroalkyl Acids in Inuit Youth and Adults in Nunavik Using a Feature Selection Tool.
Humans
Fluorocarbons
/ blood
Inuit
/ statistics & numerical data
Adult
Dietary Exposure
/ statistics & numerical data
Female
Male
Environmental Pollutants
/ blood
Adolescent
Young Adult
Alkanesulfonic Acids
/ blood
Food Contamination
/ analysis
Middle Aged
Decanoic Acids
/ blood
Environmental Exposure
/ statistics & numerical data
Biomarkers
/ blood
Diet
/ statistics & numerical data
Arctic Regions
Journal
Environmental health perspectives
ISSN: 1552-9924
Titre abrégé: Environ Health Perspect
Pays: United States
ID NLM: 0330411
Informations de publication
Date de publication:
Apr 2024
Apr 2024
Historique:
medline:
29
4
2024
pubmed:
29
4
2024
entrez:
29
4
2024
Statut:
ppublish
Résumé
Previous studies have identified the consumption of country foods (hunted/harvested foods from the land) as the primary exposure source of perfluoroalkyl acids (PFAA) in Arctic communities. However, identifying the specific foods associated with PFAA exposures is complicated due to correlation between country foods that are commonly consumed together. We used venous blood sample data and food frequency questionnaire data from the Perfluorooctanesulfonic acid (PFOS), perfluorodecanoic acid (PFDA), and perfluoroundecanoic acid (PFUnDA) were associated with frequent consumption of beluga Our study identifies specific food items contributing to environmental contaminant exposure in Indigenous or small communities relying on local subsistence foods using adaptive elastic net to prioritize responses from a complex food frequency questionnaire. In Nunavik, higher PFAA biomarker levels were primarily related to increased consumption of country foods, particularly beluga
Sections du résumé
BACKGROUND
UNASSIGNED
Previous studies have identified the consumption of country foods (hunted/harvested foods from the land) as the primary exposure source of perfluoroalkyl acids (PFAA) in Arctic communities. However, identifying the specific foods associated with PFAA exposures is complicated due to correlation between country foods that are commonly consumed together.
METHODS
UNASSIGNED
We used venous blood sample data and food frequency questionnaire data from the
RESULTS
UNASSIGNED
Perfluorooctanesulfonic acid (PFOS), perfluorodecanoic acid (PFDA), and perfluoroundecanoic acid (PFUnDA) were associated with frequent consumption of beluga
CONCLUSIONS
UNASSIGNED
Our study identifies specific food items contributing to environmental contaminant exposure in Indigenous or small communities relying on local subsistence foods using adaptive elastic net to prioritize responses from a complex food frequency questionnaire. In Nunavik, higher PFAA biomarker levels were primarily related to increased consumption of country foods, particularly beluga
Substances chimiques
Fluorocarbons
0
Environmental Pollutants
0
Alkanesulfonic Acids
0
Decanoic Acids
0
perfluorooctane sulfonic acid
9H2MAI21CL
Biomarkers
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM