The tRNA
TLR7
Valine
macrophage
short non-coding RNA
tRNA half
Journal
Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876
Informations de publication
Date de publication:
07 May 2024
07 May 2024
Historique:
medline:
29
4
2024
pubmed:
29
4
2024
entrez:
29
4
2024
Statut:
ppublish
Résumé
Toll-like receptors (TLRs) are crucial components of the innate immune system. Endosomal TLR7 recognizes single-stranded RNAs, yet its endogenous ssRNA ligands are not fully understood. We previously showed that extracellular (ex-) 5'-half molecules of tRNA
Identifiants
pubmed: 38683985
doi: 10.1073/pnas.2319569121
doi:
Substances chimiques
Toll-Like Receptor 7
0
Ligands
0
TLR7 protein, human
0
RNA, Transfer, His
0
Lipopolysaccharides
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2319569121Subventions
Organisme : HHS | NIH | National Institute of General Medical Sciences (NIGMS)
ID : GM106047
Organisme : HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI)
ID : HL150560
Organisme : HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID)
ID : AI151641
Organisme : HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID)
ID : AI168975
Organisme : HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID)
ID : AI171366
Organisme : American Cancer Society (ACS)
ID : RSG-17-059-01-RMC
Déclaration de conflit d'intérêts
Competing interests statement:The authors declare no competing interest.