Prenatal diagnosis of meningomyelocele resolves as a mature cystic teratoma in the thoracolumbar region.
Chiari
Diastematomyelia
Meningomyelocele
Neural tube defect
Teratoma
Tethered spinal cord
Journal
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
ISSN: 1433-0350
Titre abrégé: Childs Nerv Syst
Pays: Germany
ID NLM: 8503227
Informations de publication
Date de publication:
29 Apr 2024
29 Apr 2024
Historique:
received:
20
12
2023
accepted:
06
04
2024
medline:
30
4
2024
pubmed:
30
4
2024
entrez:
29
4
2024
Statut:
aheadofprint
Résumé
A mature cystic teratoma is a mass with heterogeneous appearance, consisting of adult tissue with two or three layers: endoderm, mesoderm, and ectoderm. It is a rare, benign transformation of somatic tissue most commonly found in the sacrococcygeal region and may resemble an uncomplicated spina bifida on prenatal ultrasonography. In this case report, we describe a female newborn with an extremely rare mature cystic teratoma in the thoracolumbar region. She presented prenatally with a preliminary diagnosis of meningomyelocele, diastematomyelia, and Chiari II malformation and a possible teratoma. However, a mass containing solid glandular tissues and bony calcifications approximately 3 × 4 cm in size was observed in the thoracolumbar region upon birth. During surgical resection, no nerve roots were found in the associated meningocele. The patient retained full lower body function postoperatively following surgical excision of the thecal sac and teratoma.
Identifiants
pubmed: 38684568
doi: 10.1007/s00381-024-06396-7
pii: 10.1007/s00381-024-06396-7
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024. The Author(s).
Références
Lu Y-H et al (2013) Unusual giant intraspinal teratoma in an infant. J Chin Med Assoc 76(7):411–4. https://doi.org/10.1016/j.jcma.2013.03.006
doi: 10.1016/j.jcma.2013.03.006
pubmed: 23664731
Balci M et al (2021) Mature cystic teratoma mimicking meningomyelocele. Childs Nerv Syst 37(7):2245–2249. https://doi.org/10.1007/s00381-020-05017-3
doi: 10.1007/s00381-020-05017-3
pubmed: 33404722
Mushtaq H, Kanth RR, Alam S (2018) Diastematomyelia due to spinal intradural extramedullary teratoma in an adult. Journal of Islamabad Medical & Dental College 7(3):221–224
Elmacı İ et al (2001) Diastematomyelia and spinal teratoma in an adult: case report. Neurosurg Focus 10(1):1–4
doi: 10.3171/foc.2001.10.1.10
Makary R et al (2007) Intramedullary mature teratoma of the cervical spinal cord at C1–2 associated with occult spinal dysraphism in an adult. Case report and review of the literature. J Neurosurg 6(6):579–84. https://doi.org/10.3171/spi.2007.6.6.12
doi: 10.3171/spi.2007.6.6.12
Nonomura Y, Miyamoto K, Wada E, Hosoe H, Nishimoto H, Ogura H, Shimizu K (2002) Intramedullary teratoma of the spine: report of two adult cases. Spinal Cord 40:40–43. https://doi.org/10.1038/sj.sc.3101247
doi: 10.1038/sj.sc.3101247
pubmed: 11821970
Prasad GL, Divya S (2020) A comprehensive review of adult onset spinal teratomas: analysis of factors related to outcomes and recurrences. Eur Spine J 29:221–237
doi: 10.1007/s00586-019-06037-7
pubmed: 31227969
Koen JL, McLendon RE, George TM (1998) Intradural spinal teratoma: evidence for a dysembryogenic origin: report of four cases. J Neurosurg 89(5):844–851
doi: 10.3171/jns.1998.89.5.0844
pubmed: 9817426
Pang D et al (1992) Split cord malformation: Part I: a unified theory of embryogenesis for double spinal cord malformations. Neurosurgery 31(3):451–480. https://doi.org/10.1227/00006123-199209000-00010
doi: 10.1227/00006123-199209000-00010
pubmed: 1407428
Wang H, Wang H, Yang Y, Liao S, Zheng J, McNutt MA et al (2009) Carcinoid tumour in a lumbar teratoma associated with tethered cord syndrome in an adult. Br J Neurosurg 23(2):199–202
doi: 10.1080/02688690802434848
pubmed: 19306179
Maiti TK et al (2010) Teratoma in split cord malformation: an unusual association: a report of two cases with a review of the literature. Pediatr Neurosurg 46(3):238–41. https://doi.org/10.1159/000320386
doi: 10.1159/000320386
pubmed: 21051924
Sharma MC, Jain D, Sarkar C, Suri V, Garg A, Singh M et al (2009) Spinal teratomas: a clinico-pathological study of 27 patients. Acta Neurochir 151:245–252
doi: 10.1007/s00701-009-0212-x
pubmed: 19247572
Babu R, Reynolds R, Moreno JR, Cummings TJ, Bagley CA (2014) Concurrent split cord malformation and teratoma: dysembryology, presentation, and treatment. J Clin Neurosci 21(2):212–216
doi: 10.1016/j.jocn.2013.04.027
pubmed: 24161341
Hazneci J, Bastacı F, Börekci A, Öztürk ÖÇ, İş M, Somay A et al (2022) Split cord malformation concomitant with spinal teratoma without open spinal dysraphism. Childs Nerv Syst 38(10):1977–1986
doi: 10.1007/s00381-022-05578-5
pubmed: 35687168