Glycemic and lipid control in patients with diabetes at time of myocardial infarction.

diabetes glycemic control lipid control myocardial infarction pharmacotherapy

Journal

Annales pharmaceutiques francaises
ISSN: 0003-4509
Titre abrégé: Ann Pharm Fr
Pays: France
ID NLM: 2985176R

Informations de publication

Date de publication:
27 Apr 2024
Historique:
received: 16 02 2024
revised: 22 04 2024
accepted: 24 04 2024
medline: 30 4 2024
pubmed: 30 4 2024
entrez: 30 4 2024
Statut: aheadofprint

Résumé

Cardiovascular risk is increased in patients with diabetes. Little is known about glycemic and lipid control in patients with diabetes. We aimed to assess glycemic and lipid controls in patients with diabetes at time of their myocardial infarction. All known patients with type 2 diabetes consecutively admitted for a myocardial infarction in our coronary care unit between March 1st and December 31st, 2021 were included in this retrospective study. Glycemic and lipid control was assessed through individualized target of glycated haemoglobin (HbA1c) and low-density lipoprotein cholesterol (LDL-c), respectively. At admission, the comprehensive list of chronic medications was obtained through medication reconciliation. This study included 112 patients with a median age of 72 years. Most of patients had an individualized target of HbA1c and LDL-c of 7.0% (67%) and 0.55g/L (96%), respectively. The rate of uncontrolled patients for HbA1c and LDL-c and both was 46%, 90%, and 42% respectively. The rate of patients with non-optimal glucose- and lipid-lowering medications in uncontrolled patients was 63% and 87%, respectively. The rate of inappropriate glucose- and lipid-lowering medications was 73% and 91%, respectively. We highlighted the poor glycemic and lipid control in high-risk CV patients. There is an urgent need to develop multidisciplinary approaches to optimize CV risk factors control to reduce myocardial infarction and strokes.

Identifiants

pubmed: 38685473
pii: S0003-4509(24)00067-1
doi: 10.1016/j.pharma.2024.04.010
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright © 2024. Published by Elsevier Masson SAS.

Auteurs

Christelle Lacqua (C)

Pharmacy Department, Dijon Bourgogne University Hospital, 21000 Dijon, France.

Héloïse Adam (H)

Pharmacy Department, Dijon Bourgogne University Hospital, 21000 Dijon, France.

Marianne Zeller (M)

Cardiology Department, Dijon Bourgogne University Hospital, PEC2, EA 7460, 21000 Dijon, France.

Lucie Vadot (L)

Pharmacy Department, Dijon Bourgogne University Hospital, 21000 Dijon, France.

Florence Bichat (F)

Cardiology Department, Dijon Bourgogne University Hospital, 21000 Dijon, France.

Maud Maza (M)

Cardiology Department, Dijon Bourgogne University Hospital, 21000 Dijon, France.

Yves Cottin (Y)

Cardiology Department, Dijon Bourgogne University Hospital, PEC2, EA 7460, 21000 Dijon, France.

Mathieu Boulin (M)

Department of Pharmacy, University Hospital and EPICAD LNC UMR 1231, University of Burgundy & Franche Comte, Dijon, France. Electronic address: mathieu.boulin@chu-dijon.fr.

Classifications MeSH