Outcomes and care quality metrics for people living with rheumatic heart disease and atrial fibrillation in Uganda.
Atrial fibrillation
Global health
Outcomes
Retention in care
Rheumatic heart disease
Journal
Heart rhythm O2
ISSN: 2666-5018
Titre abrégé: Heart Rhythm O2
Pays: United States
ID NLM: 101768511
Informations de publication
Date de publication:
Apr 2024
Apr 2024
Historique:
medline:
1
5
2024
pubmed:
1
5
2024
entrez:
1
5
2024
Statut:
epublish
Résumé
Atrial fibrillation (AF) is a common complication of rheumatic heart disease (RHD) and is challenging to treat in lower-resourced settings in which RHD remains endemic. We characterized demographics, treatment outcomes, and factors leading to care retention for participants with RHD and AF in Uganda. We conducted a retrospective analysis of the Uganda national RHD registry between June 2009 and May 2018. Participants with AF or atrial flutter were included. Demographics, survival, and care metrics were compared with participants without AF. Multivariable logistic regression was used to identify factors associated with retention in care among participants with AF. A total of 1530 participants with RHD were analyzed and 293 (19%) had AF. The median age was 24 (interquartile range 14-38) years. Mortality was similar in both groups (adjusted hazard ratio 1.183, Participants with RHD and AF in Uganda do not experience higher mortality than those without AF. Anticoagulation prescription rates are high. Although retention in care is poor among RHD participants, those with concurrent AF are more likely to be retained.
Sections du résumé
Background
UNASSIGNED
Atrial fibrillation (AF) is a common complication of rheumatic heart disease (RHD) and is challenging to treat in lower-resourced settings in which RHD remains endemic.
Objective
UNASSIGNED
We characterized demographics, treatment outcomes, and factors leading to care retention for participants with RHD and AF in Uganda.
Methods
UNASSIGNED
We conducted a retrospective analysis of the Uganda national RHD registry between June 2009 and May 2018. Participants with AF or atrial flutter were included. Demographics, survival, and care metrics were compared with participants without AF. Multivariable logistic regression was used to identify factors associated with retention in care among participants with AF.
Results
UNASSIGNED
A total of 1530 participants with RHD were analyzed and 293 (19%) had AF. The median age was 24 (interquartile range 14-38) years. Mortality was similar in both groups (adjusted hazard ratio 1.183,
Conclusion
UNASSIGNED
Participants with RHD and AF in Uganda do not experience higher mortality than those without AF. Anticoagulation prescription rates are high. Although retention in care is poor among RHD participants, those with concurrent AF are more likely to be retained.
Identifiants
pubmed: 38690140
doi: 10.1016/j.hroo.2024.02.002
pii: S2666-5018(24)00028-X
pmc: PMC11056452
doi:
Types de publication
Journal Article
Langues
eng
Pagination
201-208Informations de copyright
© 2024 Heart Rhythm Society. Published by Elsevier Inc.