Improved Enzymatic Production of the Fucosylated Human Milk Oligosaccharide LNFP II with GH29B α-1,3/4-l-Fucosidases.

acid/base residue flexibility molecular dynamics protein engineering transglycosylation

Journal

Journal of agricultural and food chemistry
ISSN: 1520-5118
Titre abrégé: J Agric Food Chem
Pays: United States
ID NLM: 0374755

Informations de publication

Date de publication:
01 May 2024
Historique:
medline: 1 5 2024
pubmed: 1 5 2024
entrez: 1 5 2024
Statut: aheadofprint

Résumé

Five GH29B α-1,3/4-l-fucosidases (EC 3.2.1.111) were investigated for their ability to catalyze the formation of the human milk oligosaccharide lacto-

Identifiants

DOI: 10.1021/acs.jafc.4c01547 PMID: 38691641
pubmed: 38691641
doi: 10.1021/acs.jafc.4c01547
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Yaya Yang (Y)

Section for Protein Chemistry and Enzyme Technology, Department of Biotechnology and Biomedicine, DTU Bioengineering, Technical University of Denmark, Building 221, Kgs. Lyngby DK-2800, Denmark.
School of Food and Biological Engineering, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.

Albert Thor Thorhallsson (AT)

Section for Protein Chemistry and Enzyme Technology, Department of Biotechnology and Biomedicine, DTU Bioengineering, Technical University of Denmark, Building 221, Kgs. Lyngby DK-2800, Denmark.

Carme Rovira (C)

Departament de Química Inorgànica i Orgànica & IQTCUB, Universitat de Barcelona, Barcelona 08028, Spain.
Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona 08020, Spain.
ORCID: 0000-0003-1477-5010

Jesper Holck (J)

Section for Protein Chemistry and Enzyme Technology, Department of Biotechnology and Biomedicine, DTU Bioengineering, Technical University of Denmark, Building 221, Kgs. Lyngby DK-2800, Denmark.

Anne S Meyer (AS)

Section for Protein Chemistry and Enzyme Technology, Department of Biotechnology and Biomedicine, DTU Bioengineering, Technical University of Denmark, Building 221, Kgs. Lyngby DK-2800, Denmark.
ORCID: 0000-0001-8910-9931

Huan Yang (H)

School of Food and Biological Engineering, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.

Birgitte Zeuner (B)

Section for Protein Chemistry and Enzyme Technology, Department of Biotechnology and Biomedicine, DTU Bioengineering, Technical University of Denmark, Building 221, Kgs. Lyngby DK-2800, Denmark.
ORCID: 0000-0002-8593-6742

Classifications MeSH