Fibrosis
Infrapatellar fat pad
Knee
Obesity
Osteoarthritis
PLOD2
Journal
Osteoarthritis and cartilage open
ISSN: 2665-9131
Titre abrégé: Osteoarthr Cartil Open
Pays: England
ID NLM: 101767068
Informations de publication
Date de publication:
Jun 2024
Jun 2024
Historique:
received:
13
06
2023
accepted:
06
04
2024
medline:
2
5
2024
pubmed:
2
5
2024
entrez:
2
5
2024
Statut:
epublish
Résumé
To investigate associations between obesity-linked systemic factors and gene expression indicative for the inflammatory and fibrotic processes in the infrapatellar fat pad (IFP), in a population of obese patients with end-stage knee osteoarthritis (KOA). We collected human IFPs from 48 patients with a mean body mass index (BMI) of 35.44 kg/m Univariate analysis resulted in a positive correlation between BMI and procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 ( Our study demonstrates the positive association between fat mass and
Identifiants
pubmed: 38694906
doi: 10.1016/j.ocarto.2024.100469
pii: S2665-9131(24)00036-0
pmc: PMC11061337
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100469Informations de copyright
© 2024 The Author(s).
Déclaration de conflit d'intérêts
The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.