Patient-derived tumoroids and proteomic signatures: tools for early drug discovery.


Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2024
Historique:
received: 31 01 2024
accepted: 14 03 2024
medline: 3 5 2024
pubmed: 3 5 2024
entrez: 3 5 2024
Statut: epublish

Résumé

Onco-virotherapy is an emergent treatment for cancer based on viral vectors. The therapeutic activity is based on two different mechanisms including tumor-specific oncolysis and immunostimulatory properties. In this study, we evaluated onco-virotherapy

Identifiants

pubmed: 38698850
doi: 10.3389/fimmu.2024.1379613
pmc: PMC11063793
doi:

Substances chimiques

Proteome 0
Biomarkers, Tumor 0
B7-H1 Antigen 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1379613

Informations de copyright

Copyright © 2024 Lê, Deforges, Cutolo, Lamarque, Hua, Lindner, Jain, Balloul, Benkirane-Jessel and Quéméneur.

Déclaration de conflit d'intérêts

HL, JD, SJ, JB and EQ were employed by Transgene S.A.. PC and AL were employed by Olink. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Auteurs

Hélène Lê (H)

Transgene S.A., Illkirch-Graffenstaden, France.
INSERM UMR1260, Regenerative Nanomedicine, Strasbourg, France.

Jules Deforges (J)

Transgene S.A., Illkirch-Graffenstaden, France.

Pasquale Cutolo (P)

Olink, Uppsala, Sweden.

Anissa Lamarque (A)

Olink, Uppsala, Sweden.

Guoqiang Hua (G)

INSERM UMR1260, Regenerative Nanomedicine, Strasbourg, France.

Véronique Lindner (V)

INSERM UMR1260, Regenerative Nanomedicine, Strasbourg, France.
Department of Pathology, Hopitaux Universitaires de Strasbourg, Strasbourg, France.

Shreyansh Jain (S)

Transgene S.A., Illkirch-Graffenstaden, France.

Jean-Marc Balloul (JM)

Transgene S.A., Illkirch-Graffenstaden, France.

Nadia Benkirane-Jessel (N)

INSERM UMR1260, Regenerative Nanomedicine, Strasbourg, France.

Eric Quéméneur (E)

Transgene S.A., Illkirch-Graffenstaden, France.

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Classifications MeSH